ReviewApplied microbiology and biotechnology2010
Spaceflight and modeled microgravity effects on microbial growth and virulence.
Review in Applied microbiology and biotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 1 synthesis or guideline pooled it, 157 citations in OpenAlex.
- Meta-analysis of data from spaceflight transcriptome experiments does not support the idea of a common bacterial "spaceflight response".Scientific reports · 2018Pooled it
- Evaluation of polyampholyte thin film hydrogels for the prevention ofRSC advances · 2026Article
- Assessing the Effects of Microgravity on Eukaryotic Cells Using a Statistical Thermodynamic Approach.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Adaptive transcriptional remodeling ofNpj complexity · 2026Article
- The role of extremophile microbiomes in terraforming Mars.Communications biology · 2025Review
- Biomining of lunar regolith simulant EAC-1 A with the fungus Penicillium simplicissimum.Fungal biology and biotechnology · 2025Article
- Impact of simulated microgravity in short-term evolution of an RNA bacteriophage.Frontiers in microbiology · 2025Article
- Effect ofInternational journal of microbiology · 2025Article
- Whole genome-scale assessment of gene fitness of Novosphingobium aromaticavorans during spaceflight.BMC genomics · 2023Article
- Biofilm reactors for the treatment of used water in space:potential, challenges, and future perspectives.Biofilm · 2023Article
- Article
- Biocomposite Coatings Doped with Magnesium and Zinc Ions in Chitosan Matrix for Antimicrobial Applications.Materials (Basel, Switzerland) · 2023Article
- Microbiota and probiotics: chances and challenges - a symposium report.Gut microbiome (Cambridge, England) · 2023Review
- Lab-on-a-Chip Technologies for Microgravity Simulation and Space Applications.Micromachines · 2022Review
- Simulated Microgravity Accelerates Alloy Corrosion by Aspergillus sp. via the Enhanced Production of Organic Acids.Applied and environmental microbiology · 2022Article
- Phenotypic, genomic, and transcriptomic changes in an Acinetobacter baumannii strain after spaceflight in China's Tiangong-2 space laboratory.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Article
- Article
- Melanin protects Cryptococcus neoformans from spaceflight effects.Environmental microbiology reports · 2022Article
- Long-Duration Space Travel Support Must Consider Wider Influences to Conserve Microbiota Composition and Function.Life (Basel, Switzerland) · 2022Review
- Adaptation to simulated microgravity in Streptococcus mutans.NPJ microgravity · 2022Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For unsuspecting bacteria, the difference between life and death depends upon efficient and specific responses to various stressors. Facing a much larger world, microbes are invariably challenged with ever-changing environments where temperature, pH, chemicals, and nutrients are in a constant state of flux. Only those that are able to rapidly reprogram themselves and express subsets of genes needed to overcome the stress will survive and outcompete neighboring microbes. Recently, low shear stress, emulating microgravity (MG) experienced in space, has been characterized in a number of microorganisms including fungi and prokaryotes ranging from harmless surrogate organisms to bona fide pathogens. Interestingly, MG appears to induce a plethora of effects ranging from enhanced pathogenicity in several Gram-negative enterics to enhanced biofilm formation. Furthermore, MG-exposed bacteria appeared better able to handle subsequent stressors including: osmolarity, pH, temperature, and antimicrobial challenge while yeast exhibited aberrant budding post-MG-exposure. This review will focus on MG-induced alterations of virulence in various microbes with the emphasis placed on bacteria.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.