Evidence map›Paper›PMID 19847185›Full record

Trial reportJournal of perinatology : official journal of the California Perinatal Association2010

Seven-month developmental outcomes of very low birth weight infants enrolled in a randomized controlled trial of delayed versus immediate cord clamping.

J S Mercer, B R Vohr, D A Erickson-Owens, J F Padbury, W Oh

2 registry-linked trialsOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00840983 phase1completednot on this map

Effects of Delayed Cord Clamping in Very Low Birth Weight (VLBW) Infants

TypeinterventionalSponsorUniversity of Rhode IslandRan2003 to 2006Enrolled72ConditionsBronchopulmonary Dysplasia, Necrotizing Enterocolitis, Intraventricular Hemorrhage, Late Onset Neonatal SepsisArmsdelayed cord clamping
NCT01426698 phase2completednot on this mapstarted 2011, after this paper: background citation

18 Month Follow Up of Preterm Infants Enrolled in the Cord Clamping Study

TypeinterventionalSponsorUniversity of Rhode IslandRan2011 to 2014Enrolled208ConditionsDevelopmental DelayArmsdelayed cord clamping
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 118 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Placental transfusion in preterm neonates of 30-33 weeks' gestation: a randomized controlled trial.Journal of perinatology : official journal of the California Perinatal Association · 2018
    Trial
  6. Trial
  7. Comparison of three types of intervention to enhance placental redistribution in term newborns: randomized control trial.Journal of perinatology : official journal of the California Perinatal Association · 2015
    Trial
  8. Trial
  9. Trial
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Successful implementation of an intracranial hemorrhage (ICH) bundle in reducing severe ICH: a quality improvement project.Journal of perinatology : official journal of the California Perinatal Association · 2019
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Whole-blood viscosity in the neonate: effects of gestational age, hematocrit, mean corpuscular volume and umbilical cord milking.Journal of perinatology : official journal of the California Perinatal Association · 2014
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

J S MercerCollege of Nursing, University of Rhode Island, Kingston, RI 02881, USA. jmercer@uri.edu
B R Vohr
D A Erickson-Owens
J F Padbury
W Oh
Brown University · USUniversity of Rhode Island · US

Funding

Outcomes of Delayed Cord Clamping in VLBW InfantsK23NR008027 · NINR · UNIVERSITY OF RHODE ISLAND · PI MERCER, JUDITH SMITH · 2003 to 2005
$392k
NINR NIH HHS K23 NR00078NINR NIH HHS K23 NR008027
6 · The paper itself

Abstract

objectiveThe results from our previous trial revealed that infants with delayed cord clamping (DCC) had significantly lesser intraventricular hemorrhage (IVH) and late-onset sepsis (LOS) than infants with immediate cord clamping (ICC). A priori, we hypothesized that infants with DCC would have better motor function by 7 months corrected age. STUDY

designInfants between 24 and 31 weeks were randomized to ICC or DCC and follow-up evaluation was completed at 7 months corrected age.

resultWe found no differences in the Bayley Scales of Infant Development (BSID) scores between the DCC and ICC groups. However, a regression model of effects of DCC on motor scores controlling for gestational age, IVH, bronchopulmonary dysplasia, sepsis and male gender suggested higher motor scores of male infants with DCC.

conclusionDCC at birth seems to be protective of very low birth weight male infants against motor disability at 7 months corrected age.

Indexed as

Infant, Very Low Birth WeightPerinatal CareChild DevelopmentConstrictionDevelopmental DisabilitiesFemaleFollow-Up StudiesHumansInfantInfant, NewbornInfant, PrematureMaleSex FactorsUmbilical Cord

Identifiers

PMID19847185
PMCPMC2799542
OpenAlexW2129188801

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.