Evidence map›Paper›PMID 19846593›Full record

ArticleNucleic acids research2010

REBASE--a database for DNA restriction and modification: enzymes, genes and genomes.

Richard J Roberts, Tamas Vincze, Janos Posfai, Dana Macelis

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 279 papers.

0numbers the graph read from it
0cells of the map it votes in
279citing papers in PubMed
20.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

279 citing papers in PubMed, 1,041 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  8. Antimicrobial resistance level and conjugation permissiveness shape plasmid distribution in clinical enterobacteria.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
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  10. Comparison ofEpigenomes · 2023
    Article
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  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

219 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Richard J RobertsNew England Biolabs, Inc, 240 County Road, Ipswich, MA 01938, USA.
Tamas Vincze
Janos Posfai
Dana Macelis
New England Biolabs (United States) · US

Funding

REBASE--THE RESTRICTION ENZYME DATABASEP41LM005800 · NLM · NEW ENGLAND BIOLABS, INC. · PI ROBERTS, RICHARD J · 1995 to 2011
$2.7M
FUNCTIONAL MOTIFS IN BIOLOGICAL SEQUENCESR01LM004971 · NLM · NEW ENGLAND BIOLABS, INC. · PI ROBERTS, RICHARD J. · 1988 to 1993
–
NLM NIH HHS LM04971NLM NIH HHS P41 LM005800
6 · The paper itself

Abstract

REBASE is a comprehensive database of information about restriction enzymes, DNA methyltransferases and related proteins involved in the biological process of restriction-modification (R-M). It contains fully referenced information about recognition and cleavage sites, isoschizomers, neoschizomers, commercial availability, methylation sensitivity, crystal and sequence data. Experimentally characterized homing endonucleases are also included. The fastest growing segment of REBASE contains the putative R-M systems found in the sequence databases. Comprehensive descriptions of the R-M content of all fully sequenced genomes are available including summary schematics. The contents of REBASE may be browsed from the web (http://rebase.neb.com) and selected compilations can be downloaded by ftp (ftp.neb.com). Additionally, monthly updates can be requested via email.

Indexed as

Databases, GeneticBinding SitesComputational BiologyDatabases, ProteinDNA Modification MethylasesDNA Restriction EnzymesGenome, ArchaealGenome, BacterialGenomicsInformation Storage and RetrievalInternetProtein Structure, TertiarySoftwareSubstrate SpecificityDNA Modification MethylasesDNA Restriction Enzymes

Identifiers

PMID19846593
PMCPMC2808884
OpenAlexW2133620956

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.