Evidence map›Paper›PMID 19846312›Full record

ReviewTrends in biochemical sciences2010

Plasticity of telomere maintenance mechanisms in yeast.

Neal F Lue

Abstract readReview
In one paragraph

Review in Trends in biochemical sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Article
  2. Discovery of additional ancient genome duplications in yeasts.bioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Article
  5. Frequent transitions in mating-type locus chromosomal organization inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Review
  7. Frequent transitions in mating-type locus chromosomal organization inbioRxiv : the preprint server for biology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Telomeric Repeat-Binding Factor Homologs inFrontiers in cellular and infection microbiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Neal F LueDepartment of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10065, USA. nflue@med.cornell.edu

Funding

ANALYSIS OF TELOMERASE REVERSE TRANSCRIPTASER01GM062631 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI LUE, NEAL F · 2001 to 2010
$3.0M
Telomerase function and regulation in a new model systemR01GM069507 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI LUE, NEAL F · 2004 to 2007
$1.2M
NIGMS NIH HHS GM062631NIGMS NIH HHS GM069507NIGMS NIH HHS R01 GM062631NIGMS NIH HHS R01 GM069507
6 · The paper itself

Abstract

Telomeres, the nucleoprotein structures located at linear eukaryotic chromosomal termini, are essential for chromosome stability and are maintained by the special reverse transcriptase named telomerase. In the Saccharomycotina subphylum of budding yeast, telomere repeat sequences and binding factors, as well as telomerase components, are exceptionally diverse and distinct from those found in other eukaryotes. In this survey, I report a comparative analysis of the domain structures of telomere and telomerase-related factors made possible by the recent sequencing of multiple yeast genomes. This analysis revealed both conserved and variable aspects of telomere maintenance. Based on these findings, I propose a plausible series of evolutionary events in budding yeast to account for its exceptional telomere structural divergence.

Indexed as

Chromosomal Proteins, Non-HistoneSaccharomycetalesTelomeraseTelomereChromosomal Proteins, Non-HistoneTelomerase

Identifiers

PMID19846312
PMCPMC2818170

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.