ReviewClinical reviews in allergy & immunology2010
Does the immune system induce labor? Lessons from preterm deliveries in women with autoimmune diseases.
Review in Clinical reviews in allergy & immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Thyroid autoimmunity is strongly associated with embryo quality in infertile euthyroid women receiving IVF/ICSI, especially patients with TSH values above 2.5 uIU/mL and poor ovarian response.BMC pregnancy and childbirth · 2025Article
- Expected advances in human fertility treatments and their likely translational consequences.Journal of translational medicine · 2018Review
- Whole-transcriptome analysis delineates the human placenta gene network and its associations with fetal growth.BMC genomics · 2017Article
- Redirecting reproductive immunology research toward pregnancy as a period of temporary immune tolerance.Journal of assisted reproduction and genetics · 2017Article
- Some aspects of interactivity between endocrine and immune systems required for successful reproduction.Reproductive biology and endocrinology : RB&E · 2015Article
- Endocrine autoimmune diseases and female infertility.Nature reviews. Endocrinology · 2014Review
- Evidence for a role for the adaptive immune response in human term parturition.American journal of reproductive immunology (New York, N.Y. : 1989) · 2013Article
- Decidual macrophages and their roles at the maternal-fetal interface.The Yale journal of biology and medicine · 2012Review
- Mechanisms and pathophysiology of autoimmune disease.Clinical reviews in allergy & immunology · 2012Article
- Reproductive immunology: current status and future directions (part I).Clinical reviews in allergy & immunology · 2010Article
- The impact of fetal gender on prematurity in dichorionic twin gestations after in vitro fertilization.Reproductive biology and endocrinology : RB&E · 2010Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A recent review of the literature suggested that thyroid autoimmunity is statistically associated with preterm delivery. This observation raises a number of follow-up questions, among them whether autoimmune function, in general, predisposes to premature delivery. A review of the English literature for the last 10 years, via PubMed search, finds strong supportive evidence for such a hypothesis. Since the fetal-placental unit represents a (semi) allograft within a maternal (allograft) recipient, it is reasonable to assume that it is subject to similar immunologic tolerance (and failure thereof) as solid organ transplants. As autoimmune responses represent a normal feature of tolerance failure in organ transplantation, similar autoimmune responses can also be expected with failure of tolerance of the fetal-maternal graft. The association of premature (and possibly also term) labor with autoimmune function may, therefore, be the consequence of abnormalities in normal fetal-placental tolerance, leading to uterine activation and labor.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.