ArticleDer Pathologe2009
[Pleomorphic adenoma: pitfalls and clinicopathological forms of progression].
Article in Der Pathologe, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Comprehensive comparison of salivary gland and cutaneous adnexal tumors: analogous versus discrepant clinical, terminological, histological, and molecular features : Part I.: Basic anatomy, overlapping topography, first series of related tumor entities.Virchows Archiv : an international journal of pathology · 2026Review
- [Why is the histomorphological diagnosis of small salivary gland tumours so much more difficult?]Pathologie (Heidelberg, Germany) · 2023Review
- Article
- [Updates on tumours of the salivary glands : 2017 WHO classification].Der Pathologe · 2018Review
- Notch as a Possible Cell Differentiation Factor in Pleomorphic Adenomas.International journal of medical sciences · 2015Article
- [Cutaneous adnexal and salivary gland tumours. Similarities and differences].Der Pathologe · 2014Review
- Solitary fibrous tumor with entrapment of minor salivary gland tissue: an unusual presentation that requires exclusion of pleomorphic adenoma.Head and neck pathology · 2011Article
- [Secondary high-malignant transformation of a low-malignant epithelial-myoepithelial carcinoma].Der Pathologe · 2009Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the majority of cases the diagnosis of pleomorphic adenoma (PA) is straightforward. In "monomorphic" types of PA problems may result: Epithelial-rich PA need to be distinguished from basal cell adenoma or canalicular adenoma. PA dominated by mesenchymal, spindle-shaped differentiation need to be distinguished from myoepithelioma or soft tissue tumours like schwannoma. Focal biphasic-tubular differentiation with CK7/18-positive ductal cells is good evidence for a tumour within the wide spectrum of PA. Focal peripheral pseudoinfiltration can represent physiological growth pattern of PA; this may render a difficult distinction from low-malignant carcinomas like adenoid-cystic or epithelial-myoepithelial carcinoma, harbouring also tubular structures. The different progression steps of carcinoma ex pleomorphic adenoma (CEPA), starting with intraductal carcinoma, are highly relevant with respect to prognosis and therapy. Early stages including CEPA with minor extracapsular invasion show favourable prognosis, while cases with extensive extracapsular invasion carry a dismal prognosis.
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19844715What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.