Evidence map›Paper›PMID 19844667›Full record

ReviewJournal of molecular medicine (Berlin, Germany)2010

Regulation of type 1 diabetes, tuberculosis, and asthma by parasites.

Zhugong Liu, Qian Liu, David Bleich, Padmini Salgame, William C Gause

Open access · greenAbstract readReview
In one paragraph

Review in Journal of molecular medicine (Berlin, Germany), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Diabetes-inducing effects of bronchial asthma.World journal of diabetes · 2025
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Regulation of type 2 diabetes by helminth-induced Th2 immune response.The Journal of veterinary medical science · 2017
    Article
  8. Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Zhugong LiuDepartment of Medicine, UMDNJ-New Jersey Medical School, Newark, NJ 07103, USA.
Qian Liu
David Bleich
Padmini Salgame
William C Gause
Rutgers New Jersey Medical SchoolImmune Tolerance Network · USRutgers, The State University of New Jersey · US

Funding

Heminth Modulation of MtbR01AI069395 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI SALGAME, PADMINI · 2007 to 2011
$2.8M
NIAID NIH HHS R01 AI069395
6 · The paper itself

Abstract

Helminth infection is a worldwide health problem. In addition to directly causing disease, helminthic infection also affects the incidence and progression of other diseases by exerting immune modulatory effects. In animal models, infection with helminthic parasites can prevent autoimmune diseases and allergic inflammatory diseases, but worsens protective immunity to certain infectious pathogens. In this review, we summarize current findings regarding the effects of helminth infection on type 1 diabetes, tuberculosis, and asthma and discuss possible mechanisms through which helminthic parasites modulate host immunity. Investigating these mechanisms could lead to treatment strategies that specifically modulate the immune response as well as address fundamental questions in immunobiology.

Indexed as

AnimalsAsthmaDiabetes Mellitus, Type 1HelminthiasisHost-Parasite InteractionsHumansTuberculosis

Identifiers

PMID19844667
PMCPMC2863045
OpenAlexW2155164719

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.