Evidence map›Paper›PMID 19844259›Full record

ArticleEuropean journal of human genetics : EJHG2010

Drawing the history of the Hutterite population on a genetic landscape: inference from Y-chromosome and mtDNA genotypes.

Irene Pichler, Christian Fuchsberger, Christa Platzer, Minal Calişkan, Fabio Marroni, Peter P Pramstaller, Carole Ober

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in European journal of human genetics : EJHG, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Irene PichlerInstitute of Genetic Medicine, European Academy Bozen/Bolzano, (EURAC), Bolzano, Italy; Affiliated Institute of the University of Lübeck, Germany. irene.pichler@eurac.edu [corrected]
Christian Fuchsberger
Christa Platzer
Minal Calişkan
Fabio Marroni
Peter P Pramstaller
Carole Ober
Eurac Research · ITUniversity of Lübeck · DEUniversity of Chicago · US

Funding

MOLECULAR GENETIC STUDIES OF FERTILITY IN THE HUTTERITESR01HD021244 · NICHD · UNIVERSITY OF CHICAGO · PI OBER, CAROLE · 1986 to 2011
$3.0M
NICHD NIH HHS HD21244NICHD NIH HHS R01 HD021244
6 · The paper itself

Abstract

Although the North American Hutterites trace their origins to South Tyrol, no attempts have been made to examine the genetic migration history of the Hutterites before emigrating to the United States in the 1870s. To investigate this, we studied 9 microsatellite loci and 11 unique event polymorphism (UEP) markers on the Y-chromosome, the hypervariable region I (HVRI) of the mitochondrial DNA (mtDNA), as well as the complete mtDNA genome of Hutterite and South Tyrolean samples. Only 6 out of 14 Y-chromosome UEP+microsatellite haplotypes and 3 out of 11 mitochondrial haplotypes that were present in the Hutterites were also present in the South Tyrolean population. The phylogenetic relationships inferred from Y-chromosome and mtDNA databases show that the Hutterites have a unique genetic background related to a similar extent to central and eastern European populations. An admixture analysis indicates, however, a relatively high genetic contribution of central European populations to the Hutterite gene pool. These results are consistent with historical records on Hutterite migrations and demographic history. In addition, our data reveal similar numbers of Y and mitochondrial haplotypes in Hutterite male and female founders, respectively. The Hutterite male and female gene pools are similar with respect to genetic diversity and genetic distance measures and comparable with respect to their origins, suggesting a similar evolutionary history.

Indexed as

Genetics, PopulationChromosomes, Human, YDNA, MitochondrialEmigration and ImmigrationFemaleGenetic VariationGenotypeHaplotypesHumansMalePolymorphism, GeneticDNA, Mitochondrial

Identifiers

PMID19844259
PMCPMC2987252
OpenAlexW2001567538

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.