ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2009
Breast cancer recurrence in older women five to ten years after diagnosis.
Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 44 citations in OpenAlex.
- Protocol and recruitment results from a randomized controlled trial comparing group phone-based versus newsletter interventions for weight loss maintenance among rural breast cancer survivors.Contemporary clinical trials · 2014Trial
- Cytokine Regulation of the Bone Pre- and Metastatic Niches: Implications for Breast Cancer Dormancy.Cells · 2026Review
- First mammogram-detected cancers portend worse survival in young women diagnosed with breast cancer.Breast cancer research and treatment · 2025Article
- miR-106b as an emerging therapeutic target in cancer.Genes & diseases · 2022Review
- Breast cancer recurrence 27 years after full recovery; A case report with literature review.International journal of surgery case reports · 2022Article
- Mammography use in relation to comorbidities and functional limitations among older breast cancer survivors.Journal of cancer survivorship : research and practice · 2021Article
- Collaborating on Data, Science, and Infrastructure: The 20-Year Journey of the Cancer Research Network.EGEMS (Washington, DC) · 2019Review
- Identifying Breast Cancer Distant Recurrences from Electronic Health Records Using Machine Learning.Journal of healthcare informatics research · 2019Article
- Breast Cancer Survivors' Perceptions of Prevention versus Control of Future Cancer Recurrence.International journal of breast cancer · 2019Article
- Using natural language processing and machine learning to identify breast cancer local recurrence.BMC bioinformatics · 2018Article
- Stanniocalcin Expression as a Predictor of Late Breast Cancer Recurrence.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2018Article
- The Augusta, Georgia Breast Cancer Survivor Study.Journal of cancer treatment & diagnosis · 2018Article
- Contralateral Breast Cancer Event Detection Using Nature Language Processing.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2017Article
- Emerging therapeutic targets in metastatic progression: A focus on breast cancer.Pharmacology & therapeutics · 2016Review
- Long-Term Safety of Letrozole and Gonadotropin Stimulation for Fertility Preservation in Women With Breast Cancer.The Journal of clinical endocrinology and metabolism · 2016Article
- Beliefs and Behaviors about Breast Cancer Recurrence Risk Reduction among African American Breast Cancer Survivors.International journal of environmental research and public health · 2015Article
- The differences of clinicopathological factors for breast cancer in respect to time of recurrence and effect on recurrence-free survival.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2015Article
- Incident comorbidities and all-cause mortality among 5-year survivors of Stage I and II breast cancer diagnosed at age 65 or older: a prospective-matched cohort study.Breast cancer research and treatment · 2014Article
- Race and breast cancer survival by intrinsic subtype based on PAM50 gene expression.Breast cancer research and treatment · 2014Article
- A nested case-control study of adjuvant hormonal therapy persistence and compliance, and early breast cancer recurrence in women with stage I-III breast cancer.British journal of cancer · 2013Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
Little is known about the risk of recurrence >5 years after diagnosis among older breast cancer survivors. A community-based population of women >or=65 years diagnosed with early-stage breast cancer who survived disease free for 5 years was followed for 5 additional years or until a diagnosis of breast cancer recurrence, second primary, death, or loss to follow-up. These 5-year disease-free survivors (N = 1,277) had primary breast cancers that were node negative (77%) and estrogen receptor positive or unknown (86%). Five percent (n = 61) developed a recurrence between 5 and 10 years after diagnosis: 25% local, 9.8% regional, and 66% distant. Women who were node positive [hazard ratio (HR), 3.9; 95% confidence interval (95% CI), 1.5-10], had poorly differentiated tumors (HR, 2.5; 95% CI, 0.9-6.6), or who received breast conserving surgery without radiation therapy (HR, 2.4; 95% CI, 1.0-5.8) had higher recurrence rates compared with node negative, well differentiated, and receipt of mastectomy, respectively. Not receiving adjuvant tamoxifen, compared with receiving adjuvant tamoxifen, was also positively associated with late recurrence among women with estrogen receptor-positive/unknown tumors. Although relatively few women experience a late recurrence, most recurrences present as advanced disease, which is difficult to treat in older women. This study of late recurrence emphasizes that the risk, although small, is not negligible even in this group at high risk of death due to competing causes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.