ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2010
Potentially inappropriate medication use in older adults with mild cognitive impairment.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Prevalence of Use of Potentially Inappropriate Medications Among Older Adults Worldwide: A Systematic Review and Meta-Analysis.JAMA network open · 2023Pooled it
- Factors associated with potentially inappropriate medication use in community-dwelling older adults in the United States: a systematic review.The International journal of pharmacy practice · 2019Pooled it
- Inappropriate Drug Use in People with Cognitive Impairment and Dementia: A Systematic Review.Current clinical pharmacology · 2015Pooled it
- The impact of family caregivers on potentially inappropriate medication use in noninstitutionalized older adults with dementia.The American journal of geriatric pharmacotherapy · 2012Trial
- Potentially inappropriate medications use in a psychiatric elderly care hospital: A cross-sectional study using Beers criteria.Health science reports · 2023Article
- Sleep Disorders in Mild Cognitive Impairment.Cureus · 2023Review
- The Prevalence of Polypharmacy and Potentially Inappropriate Medications and Its Relationship with Cognitive Status in Portuguese Institutionalized Older Adults: A Cross-Sectional Study.International journal of environmental research and public health · 2022Article
- Article
- Use of Anti-Dementia Drugs Reduces the Risk of Potentially Inappropriate Medications: A Secondary Analysis of a Nationwide Survey of Prescribing Pharmacies.Dementia and geriatric cognitive disorders · 2020Article
- Characteristics of Mild Cognitive Impairment in Northern Japanese Community-Dwellers from the ORANGE Registry.Journal of clinical medicine · 2019Article
- Treatment of Sleep Disturbance May Reduce the Risk of Future Probable Alzheimer's Disease.Journal of aging and health · 2019Article
- Mild cognitive impairment: associations with sleep disturbance, apolipoprotein e4, and sleep medications.Sleep medicine · 2018Article
- Use of Potentially Inappropriate Medications in People With Dementia in Vietnam and Its Associated Factors.American journal of Alzheimer's disease and other dementias · 2018Article
- Effects of electroacupuncture on bladder and bowel function in patients with transverse myelitis: a prospective observational study.Acupuncture in medicine : journal of the British Medical Acupuncture Society · 2018Observational
- Racial and ethnic differences in psychotropic medication use among community-dwelling persons with dementia in the United States.Aging & mental health · 2018Article
- Prevalence and Variability in Medications Contributing to Polypharmacy in Long-Term Care Facilities.Drugs - real world outcomes · 2017Article
- An evaluation of the prevalence of potentially inappropriate medications in older people with cognitive impairment living in Northern Sweden using the EU(7)-PIM list.European journal of clinical pharmacology · 2017Article
- Risk Factors for Initiation of Potentially Inappropriate Medications in Community-Dwelling Older Adults with and without Alzheimer's Disease.Drugs & aging · 2017Article
- Potentially Inappropriate Medications and Anticholinergic Burden in Older People Attending Memory Clinics in Australia.Drugs & aging · 2016Article
- Long-term cognitive and functional effects of potentially inappropriate medications in older women.The journals of gerontology. Series A, Biological sciences and medical sciences · 2014Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPatients with mild cognitive impairment (MCI) may be especially vulnerable to the side effects of potentially inappropriate medications (PIMs), especially those that impair cognition.
methodsWe conducted a cross-sectional study to determine the prevalence of PIM use among 689 patients with MCI. We used the 2003 Beers Criteria for cognitive impairment to identify PIMs. We then determined if certain patients were more likely to use PIMs.
resultsThere were 143 (20.8%) patients with MCI taking a PIM: 108 (15.7%) patients were taking one PIM and 35 (5.1%) patients were taking two or more PIMs. The most common PIMs were anticholinergics (35.7%) and benzodiazepines (31.5%). Patients were more likely to be taking PIMs if they were women and were taking a greater number of medications and less likely if they had a history of myocardial infarction.
conclusionsPatients with MCI are frequently taking PIMs that may negatively affect cognition. Future research is needed to assess whether cognitive impairment symptoms are improved if PIM use is reduced.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.