ReviewAAPS PharmSciTech2009
Organic-inorganic composites for bone drug delivery.
Review in AAPS PharmSciTech, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Injectable antibacterial Ag-HA/ GelMA hydrogel for bone tissue engineering.Frontiers in bioengineering and biotechnology · 2023Article
- Recent Research on Hybrid Hydrogels for Infection Treatment and Bone Repair.Gels (Basel, Switzerland) · 2022Review
- Multi-Dimensional Printing for Bone Tissue Engineering.Advanced healthcare materials · 2021Review
- Bone-Induced Expression of Integrin β3 Enables Targeted Nanotherapy of Breast Cancer Metastases.Cancer research · 2017Article
- Vancomycin-loaded HPMC microparticles embedded within injectable thermosensitive chitosan hydrogels.Progress in biomaterials · 2017Article
- Insights on the properties of levofloxacin-adsorbed Sr- and Mg-doped calcium phosphate powders.Journal of materials science. Materials in medicine · 2016Article
- Vancomycin containing PLLA/β-TCP controls experimental osteomyelitis in vivo.Journal of orthopaedic surgery and research · 2014Article
- Multifunctional materials for bone cancer treatment.International journal of nanomedicine · 2014Review
- Tetracycline-encapsulated P(3HB) microsphere-coated 45S5 Bioglass(®)-based scaffolds for bone tissue engineering.Journal of materials science. Materials in medicine · 2013Article
- Metallic ions as therapeutic agents in tissue engineering scaffolds: an overview of their biological applications and strategies for new developments.Journal of the Royal Society, Interface · 2012Review
- Characterization of drug-release kinetics in trabecular bone from titania nanotube implants.International journal of nanomedicine · 2012Article
- Porous bioactive glass scaffolds for local drug delivery in osteomyelitis: development and in vitro characterization.AAPS PharmSciTech · 2010Article
- Development of porous HAp and β-TCP scaffolds by starch consolidation with foaming method and drug-chitosan bilayered scaffold based drug delivery system.Journal of materials science. Materials in medicine · 2010Article
- Development of new localized drug delivery system based on ceftriaxone-sulbactam composite drug impregnated porous hydroxyapatite: a systematic approach for in vitro and in vivo animal trial.Pharmaceutical research · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review paper attempts to provide an overview in the fabrication and application of organic-inorganic based composites in the field of local drug delivery for bone. The concept of local drug delivery exists for a few decades. However, local drug delivery in bone and specially application of composites for delivery of drugs to bone is an area for potential research interest in the recent time. The advantages attained by an organic-inorganic composite when compared to its individual components include their ability to release drug, adopting to the natural environment and supporting local area until complete bone regeneration, which make them carriers of interest for local drug delivery for bone.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.