Evidence map›Paper›PMID 19841915›Full record

ArticleEuropean journal of clinical pharmacology2010

Perception of risk regarding the use of medications and other exposures during pregnancy.

Hedvig Nordeng, Eivind Ystrøm, Adrienne Einarson

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Article in European journal of clinical pharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  13. Making decisions about antidepressant use during pregnancy: a qualitative interview study of a sample of women in the UK.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
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43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hedvig NordengDepartment of Pharmacy, School of Pharmacy, University of Oslo, Oslo, Norway. h.m.e.nordeng@farmasi.uio.no
Eivind Ystrøm
Adrienne Einarson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPerception of risk may impact a woman's decision to take a needed drug during pregnancy. There is a paucity of research on this topic in the literature.

objectives(1) To evaluate the perception of risk of 17 commonly used drugs and other substances by pregnant women. (2) To investigate which sources of information regarding exposures during pregnancy were most commonly used by women.

methodsA questionnaire was developed through the University of Oslo's website for Internet surveys and posted on four Web pages used by pregnant women and mothers, from mid-September 2008 through October 2008. The inclusion criteria included women who were (1) pregnant or 2) a mother of a child less than 5 years old.

resultsA total of 1,793 eligible women completed the questionnaire. Most women overestimated the teratogenic risk associated with all the drugs during pregnancy. Characteristics of the women that were associated with a high perception of risk were primiparity, higher age, higher education, and choosing not to use a drug during pregnancy. More than 80% of the women had used drugs during pregnancy, mostly paracetamol, penicillins and reflux medications. The physician, the product information leaflet and the pharmacist were the three most frequently used sources of information.

conclusionWomen overestimate the risk of drug use and other exposures during pregnancy. Therefore, it is important for health care providers to use evidence-based information, to reduce unnecessary anxiety, and to ensure safe and appropriate treatment during pregnancy.

Indexed as

Drug-Related Side Effects and Adverse ReactionsHealth Knowledge, Attitudes, PracticeRisk AssessmentAbnormalities, Drug-InducedAdolescentAdultBreast FeedingFemaleHumansInternetLife StyleMaternal ExposureMiddle AgedMothersPregnancyPregnancy Complications

Identifiers

PMID19841915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.