Evidence map›Paper›PMID 19841850›Full record

ReviewJournal of molecular evolution2009

Optimization models and the structure of the genetic code.

J L Jestin, A Kempf

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of molecular evolution, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Self-similarity and the maximum entropy principle in the genetic code.Theory in biosciences = Theorie in den Biowissenschaften · 2023
    Article
  2. The Self-Referential Genetic Code is Biologic and Includes the Error Minimization Property.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2015
    Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

J L JestinDépartement de Biologie Structurale et Chimie, Institut Pasteur, CNRS, 25 rue du Dr. Roux, 75724, Paris 15, France. jjestin@pasteur.fr
A Kempf

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The codon assignment of the quasi-universal genetic code can be assumed to have resulted from the evolutionary pressures that prevailed when the code was still evolving. Here, we review studies of the structure of the genetic code based on optimization models. We also review studies that, from the structure of the code, attempt to derive aspects of the primordial circumstances in which the genetic code froze. Different rationales are summarized, compared with experimental data, discussed in the context of the transition from a RNA world to a DNA-protein world, and linked to the emergence of the last universal common ancestor.

Indexed as

Evolution, MolecularGenetic CodeModels, GeneticOrigin of LifeAmino AcidsAnimalsCodonDNAHumansMutationProteinsRNASelection, GeneticAmino AcidsCodonDNAProteinsRNA

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.