ArticleNature immunology2009
NDP52: the missing link between ubiquitinated bacteria and autophagy.
Article in Nature immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 34 citations in OpenAlex.
- Article
- Identification of autophagy receptors for the Crohn's disease-associated adherent-invasiveFrontiers in cellular and infection microbiology · 2024Article
- USP8 inhibition regulates autophagy flux and controlsFrontiers in cellular and infection microbiology · 2023Article
- The Role of Autophagy and Autophagy Receptor NDP52 in Microbial Infections.International journal of molecular sciences · 2020Review
- Review
- Inhibition of the ULK1 protein complex suppressesThe Journal of biological chemistry · 2019Article
- Autophagy and Ubiquitination inFrontiers in cellular and infection microbiology · 2018Review
- Biomarkers in inflammatory bowel diseases: insight into diagnosis, prognosis and treatment.Gastroenterology and hepatology from bed to bench · 2017Review
- Macrophage-Microbe Interactions: Lessons from the Zebrafish Model.Frontiers in immunology · 2017Review
- Molecular Analysis of Inflammatory Bowel Disease: Clinically Useful Tools for Diagnosis, Response Prediction, and Monitoring of Targeted Therapy.Molecular diagnosis & therapy · 2015Review
- Article
- Review
- Tau clearance mechanisms and their possible role in the pathogenesis of Alzheimer disease.Frontiers in neurology · 2013Review
- Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies.Gastroenterology · 2013Article
- Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress.Cellular and molecular life sciences : CMLS · 2013Review
- Structural basis for recognition of autophagic receptor NDP52 by the sugar receptor galectin-8.Nature communications · 2013Article
- The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole.Biology open · 2012Article
- Mitochondria removal by autophagy.Autophagy · 2011Review
- Identification of an autophagy defect in smokers' alveolar macrophages.Journal of immunology (Baltimore, Md. : 1950) · 2010Article
Corrections and comments
- Comment on
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Mammalian cells ubiquitinate bacteria that erroneously enter the cytosol and target these intruding microbes for destruction by autophagy. New work shows that the protein NDP52 directly binds to ubiquitinated bacteria and facilitates the assembly of an autophagic membrane that surrounds these invaders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.