Evidence map›Paper›PMID 19841622›Full record

ArticleNature chemical biology2009

Post-reductionist protein science, or putting Humpty Dumpty back together again.

Lila M Gierasch, Anne Gershenson

Abstract read
In one paragraph

Article in Nature chemical biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Chemical interactions modulate λProtein science : a publication of the Protein Society · 2023
    Article
  5. Article
  6. Threading single proteins through pores to compare their energy landscapes.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. Article
  8. Article
  9. Insights into Protein Stability in Cell Lysate byChembiochem : a European journal of chemical biology · 2020
    Article
  10. Article
  11. Art and Science of the Cellular Mesoscale.Trends in biochemical sciences · 2020
    Review
  12. An in vitro mimic of in-cell solvation for protein folding studies.Protein science : a publication of the Protein Society · 2020
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Lila M GieraschDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, USA. gierasch@biochem.umass.edu
Anne Gershenson

Funding

NIH DIRECTOR'S PIONEER AWARDDP1OD000945 · OD · UNIVERSITY OF MASSACHUSETTS AMHERST · PI GIERASCH, LILA M · 2006 to 2010
$3.9M
NIH HHS DP1 OD000945
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BacteriaBacterial ProteinsComputational BiologyEscherichia coliIntracellular SpaceMicroscopy, Electron, ScanningProteinsBacterial ProteinsProteins

Identifiers

PMID19841622
PMCPMC2904569

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.