Evidence map›Paper›PMID 19841143›Full record

ArticleAntimicrobial agents and chemotherapy2010

Assessment of the in vitro kinetic activity of caspofungin against Candida glabrata.

V Nagappan, D Boikov, J A Vazquez

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

V NagappanOakwood Hospital, Dearborn, Michigan, USA.
D Boikov
J A Vazquez

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Echinocandins have become the drug of choice in infections caused by Candida glabrata. The objective of this study was to evaluate the in vitro activity of caspofungin alone and in combination against C. glabrata. In vitro assays demonstrated that caspofungin alone showed excellent fungicidal activity against C. glabrata, including fluconazole-resistant strains. The combination of caspofungin and azole antifungals showed potential synergy against C. glabrata. Overall, caspofungin demonstrated excellent in vitro activity, alone and in combination, against strains of C. glabrata.

Indexed as

Amphotericin BAntifungal AgentsAzolesCandida glabrataCaspofunginDrug CombinationsDrug Resistance, FungalDrug SynergismEchinocandinsFluconazoleKineticsLipopeptidesMicrobial Sensitivity TestsPyrimidinesTime FactorsTriazolesAmphotericin BAntifungal AgentsAzolesCaspofunginDrug CombinationsEchinocandinsFluconazoleLipopeptidesPyrimidinesTriazolesVoriconazole

Identifiers

PMID19841143
PMCPMC2798515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.