Evidence map›Paper›PMID 19841135›Full record

ArticleThe Journal of cell biology2009

It takes two to tango to the melanosome.

Aparna Lakkaraju, Jose Maria Carvajal-Gonzalez, Enrique Rodriguez-Boulan

Open access · hybridAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of cell biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Adaptor protein complexes 1 and 3 are essential for generation of synaptic vesicles from activity-dependent bulk endosomes.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Aparna LakkarajuMargaret M. Dyson Vision Research Institute, Weill Medical College, Cornell University, New York, NY 10065, USA.
Jose Maria Carvajal-Gonzalez
Enrique Rodriguez-Boulan
Dyson (United Kingdom) · GBSingapore Eye Research Institute · SG

Funding

SORTING OF PLASMA MEMBRANE PROTEINS IN EPITHELIAL CELLSR01GM034107 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI RODRIGUEZ-BOULAN, ENRIQUE J · 1985 to 2019
$9.6M
NIGMS NIH HHS R01 GM034107
6 · The paper itself

Abstract

The role of clathrin adaptor proteins in sorting cargo in the biosynthetic and recycling routes is an area of intense research. In this issue, Delevoye et al. (2009. J. Cell Biol. doi:10.1083/jcb.200907122) show that a close interaction between the clathrin adaptor AP-1 and a kinesin motor KIF13A is essential for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes and for organelle biogenesis.

Indexed as

Adaptor Protein Complex 1AnimalsEndosomesHumansKinesinsMelanosomesAdaptor Protein Complex 1KIF13A protein, humanKinesins

Identifiers

PMID19841135
PMCPMC2768836
OpenAlexW2165261262

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.