Evidence map›Paper›PMID 19841134›Full record

ArticleThe Journal of cell biology2009

Keratins and protein synthesis: the plot thickens.

Juliane C Kellner, Pierre A Coulombe

Open access · hybridAbstract readComment
In one paragraph

Article in The Journal of cell biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Damaged Keratin Filament Network Caused byFrontiers in genetics · 2021
    Article
  2. Types I and II Keratin Intermediate Filaments.Cold Spring Harbor perspectives in biology · 2018
    Review
  3. Epithelial Keratins Modulate cMet Expression and Signaling and Promote InlB-MediatedFrontiers in cellular and infection microbiology · 2018
    Article
  4. Gene expression profiling in pachyonychia congenita skin.Journal of dermatological science · 2015
    Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Juliane C KellnerDepartment of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 20723, USA.
Pierre A Coulombe
Johns Hopkins University · US

Funding

Non-Canonical Functions of Keratin Proteins in SkinR01AR044232 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COULOMBE, PIERRE · 1996 to 2020
$8.6M
NIAMS NIH HHS R01 AR044232
6 · The paper itself

Abstract

In addition to protecting epithelial cells from mechanical stress, keratins regulate cytoarchitecture, cell growth, proliferation, apoptosis, and organelle transport. In this issue, Vijayaraj et al. (2009. J. Cell Biol. doi:10.1083/jcb.200906094) expand our understanding of how keratin proteins participate in the regulation of protein synthesis through their analysis of mice lacking the entire type II keratin gene cluster.

Indexed as

Protein BiosynthesisAdaptor Proteins, Signal TransducingAdenylate KinaseAnimalsCarrier ProteinsGlucose Transport Proteins, FacilitativeHumansKeratins, Type IIMiceRegulatory-Associated Protein of mTORAdaptor Proteins, Signal TransducingAdenylate KinaseCarrier ProteinsGlucose Transport Proteins, FacilitativeKeratins, Type IIRegulatory-Associated Protein of mTORRptor protein, mouse

Identifiers

PMID19841134
PMCPMC2768833
OpenAlexW2135905861

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.