Evidence map›Paper›PMID 19840520›Full record

ReviewCurrent oncology reports2009

Neuroblastoma: biology and staging.

Sabine Mueller, Katherine K Matthay

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current oncology reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 107 citations in OpenAlex.

  1. Article
  2. [European journal of nuclear medicine and molecular imaging · 2025
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  10. miR-15a and miR-15b modulate natural killer and CD8Molecular therapy oncolytics · 2022
    Article
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  12. Pyrido[2',1':2,3]imidazo[4,5-Pharmaceuticals (Basel, Switzerland) · 2021
    Article
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  16. Review
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  19. Current Consensus on I-131 MIBG Therapy.Nuclear medicine and molecular imaging · 2018
    Review
  20. Individualized risk assessment in neuroblastoma: does the tumoral metabolic activity onEuropean journal of nuclear medicine and molecular imaging · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sabine MuellerDepartment of Pediatric Hematology-Oncology, University of California, San Francisco School of Medicine, M647, 505 Parnassus Avenue, San Francisco, CA 94143, USA.
Katherine K Matthay
University of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroblastoma is the most common extracranial tumor of childhood, with about 650 new cases each year in the United States. The clinical course of neuroblastoma is variable and depends on age at diagnosis, staging, histology, and specific genetic abnormalities, such as MYCN oncogene amplification or aberrations of chromosome 1p or 11q. A subset of tumors will undergo spontaneous regression, whereas others progress despite aggressive therapy. The varied clinical behavior reflects genetic heterogeneity, with many possible gene candidates identified in studies using comparative genetic hybridization arrays, RNA expression microarrays, and genome-wide association studies. Recent studies implicated the anaplastic lymphoma kinase gene in the tumorigenesis of many familial and some sporadic cases of neuroblastoma. The International Neuroblastoma Risk Group developed a new staging and risk classification, with recommendations for analysis of biological markers in neuroblastoma. This review discusses the biology of these tumors, current and new risk classification, and staging recommendations, with a brief outline of preferred treatment strategies.

Indexed as

Genetic Predisposition to DiseaseLoss of HeterozygosityNeuroblastomaAge of OnsetChromosome AberrationsChromosomes, Human, Pair 1Chromosomes, Human, Pair 11Gene AmplificationHumansNeoplasm StagingPrognosisRisk

Identifiers

PMID19840520
OpenAlexW1975197349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.