Evidence map›Paper›PMID 19838167›Full record

ReviewNature2009

What recent ribosome structures have revealed about the mechanism of translation.

T Martin Schmeing, V Ramakrishnan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 313 papers.

0numbers the graph read from it
0cells of the map it votes in
313citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

313 citing papers in PubMed.

  1. Article
  2. Transient ion-mediated interactions regulate subunit rotation in a eukaryotic ribosome.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. A cascade of structural rearrangements positions peptide release factor 2 for polypeptide hydrolysis on the ribosome.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
  7. Multi-channel smFRET study reveals a compact conformation of EF-G on the ribosome.The international journal of biochemistry & cell biology · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Cooperative and Independent Functionality of tmRNA and SmpB inInternational journal of molecular sciences · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. YfmR is a translation factor that prevents ribosome stalling and cell death in the absence of EF-P.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  20. Human mtDNA-Encoded Long ncRNAs: Knotty Molecules and Complex Functions.International journal of molecular sciences · 2024
    Review

253 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

T Martin SchmeingMRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK. schmeing@mrc-lmb.cam.ac.uk
V Ramakrishnan

Funding

Medical Research Council MC_U105184332Wellcome Trust
6 · The paper itself

Abstract

The high-resolution structures of ribosomal subunits published in 2000 have revolutionized the field of protein translation. They facilitated the determination and interpretation of functional complexes of the ribosome by crystallography and electron microscopy. Knowledge of the precise positions of residues in the ribosome in various states has facilitated increasingly sophisticated biochemical and genetic experiments, as well as the use of new methods such as single-molecule kinetics. In this review, we discuss how the interaction between structural and functional studies over the last decade has led to a deeper understanding of the complex mechanisms underlying translation.

Indexed as

Bacterial ProteinsBiocatalysisProtein BiosynthesisRibosomal ProteinsRibosomesStructure-Activity RelationshipBacterial ProteinsRibosomal Proteins

Identifiers

PMID19838167

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.