Evidence map›Paper›PMID 19837791›Full record

Trial reportDiabetes care2010

Effectiveness of continuous glucose monitoring in a clinical care environment: evidence from the Juvenile Diabetes Research Foundation continuous glucose monitoring (JDRF-CGM) trial.

Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Diabetes care, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03736083 (Introducing Continuous Glucose Monitoring Technology at Diagnosis in Pediatric Type 1 Diabetes), which is not on this map. Cited by 161 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
161citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03736083 nawithdrawnnot on this mapstarted 2019, after this paper: background citation

Introducing Continuous Glucose Monitoring Technology at Diagnosis in Pediatric Type 1 Diabetes: A Proof of Concept Study

TypeinterventionalSponsorUniversity of FloridaRan2019 to 2020Enrolled0ConditionsType1diabetes, HypoglycemiaArmsFreestyle Libre Blood Glucose Monitor
3 · Its place in the literature

Who cites it

161 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  6. Hypoglycemia in critically ill children.Journal of diabetes science and technology · 2012
    Pooled it
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  9. Targeting glucose control in preterm infants: pilot studies of continuous glucose monitoring.Archives of disease in childhood. Fetal and neonatal edition · 2019
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  13. Acceptability of Implantable Continuous Glucose Monitoring Sensor.Journal of diabetes science and technology · 2018
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101 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Groupjdrfapp@jaeb.org

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine whether continuous glucose monitoring (CGM) is effective in the management of type 1 diabetes when implemented in a manner that more closely approximates clinical practice. RESEARCH DESIGN AND

methodsAfter completion of a 6-month randomized controlled trial (RCT) evaluating CGM in children, adolescents, and adults with type 1 diabetes, CGM was initiated in the trial's control group with less intensive training and follow-up than was included in the RCT. Subjects had an outpatient training session, two follow-up phone calls, and outpatient visits at 1, 4, 13, and 26 weeks. For subjects with baseline A1C > or =7.0%, the primary outcome was change in A1C at 6 months.

resultsCGM use decreased from a median of 7.0 days/week in the first month in the > or =25-year-old group, 6.3 days/week in the 15-24 year olds, and 6.8 days/week in the 8-14 year olds to 6.5, 3.3, and 3.7 days/week in the 6th month, respectively (P < 0.001 for each age-group). Among subjects with baseline A1C > or =7.0%, CGM use was associated with A1C reduction after 6 months (P = 0.02 adjusted for age-group). Severe hypoglycemia decreased from 27.7 events per 100 person-years in the 6-month control phase of the RCT to 15.0 events per 100 person-years in the 6-month follow-up CGM phase (P = 0.08).

conclusionsFrequent use of CGM in a clinical care setting may improve A1C and reduce episodes of hypoglycemia. However, sustained frequent use of CGM is less likely in children and adolescents than in adults.

Indexed as

AdolescentAdultBlood GlucoseChildDiabetes Mellitus, Type 1Glycated HemoglobinHumansHypoglycemiaHypoglycemic AgentsInsulinMonitoring, AmbulatoryYoung AdultBlood GlucoseGlycated HemoglobinHypoglycemic AgentsInsulin

Identifiers

PMID19837791
PMCPMC2797966

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.