Evidence map›Paper›PMID 19837532›Full record

ReviewJournal of vascular surgery2010

Adaptive changes in autogenous vein grafts for arterial reconstruction: clinical implications.

Christopher D Owens

Abstract readReview
In one paragraph

Review in Journal of vascular surgery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Mechanical Activation of cPLA2 Impedes Fatty Acid β-Oxidation in Vein Grafts.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  10. Article
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  12. Article
  13. Review
  14. Article
  15. Article
  16. Association of CHAHerz · 2022
    Article
  17. Review
  18. Article
  19. Review
  20. Review

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Christopher D OwensDivision of Vascular and Endovascular Surgery, University of California San Francisco, San Francisco, CA 94143, USA. christopher.owens@ucsfmedctr.org

Funding

Inflammation and Insulin Resistance in PADR01HL075771 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CREAGER, MARK A · 2003 to 2007
$4.5M
Endothelial Function and Peripheral Vein Bypass Graft RemodelingK23HL092163 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI OWENS, CHRISTOPHER DEAN · 2008 to 2012
$635k
NHLBI NIH HHS K23 HL092163NHLBI NIH HHS K23 HL 92163NHLBI NIH HHS R01 HL075771NHLBI NIH HHS R01 HL75771
6 · The paper itself

Abstract

For patients with the most severe manifestations of lower extremity arterial occlusive disease, bypass surgery using autogenous vein has been the most durable reconstruction. However, the incidence of bypass graft stenosis and graft failure remains substantial and wholesale improvements in patency are lacking. One potential explanation is that stenosis arises not only from over exuberant intimal hyperplasia, but also due to insufficient adaptation or remodeling of the vein to the arterial environment. Although in vivo human studies are difficult to conduct, recent advances in imaging technology have made possible a more comprehensive structural examination of vein bypass maturation. This review summarizes recent translational efforts to understand the structural and functional properties of human vein grafts and places it within the context of the rich existing literature of vein graft failure.

Indexed as

Vascular PatencyAnimalsArterial Occlusive DiseasesConstriction, PathologicEndothelium, VascularGraft Occlusion, VascularGraft SurvivalHumansInflammationLower ExtremitySaphenous VeinSeverity of Illness IndexTime FactorsTranslational Research, BiomedicalTransplantation, AutologousTreatment Outcome

Identifiers

PMID19837532
PMCPMC2834835

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.