Evidence map›Paper›PMID 19836492›Full record

ReviewThe Surgical clinics of North America2009

Sporadic and familial medullary thyroid carcinoma: state of the art.

Tricia A Moo-Young, Amber L Traugott, Jeffrey F Moley

Abstract readReview
In one paragraph

Review in The Surgical clinics of North America, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 75 citations in OpenAlex.

  1. Mechanistic insights into ferroptosis in thyroid cancer and its therapeutic implications.Apoptosis : an international journal on programmed cell death · 2026
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  15. Advanced thyroid cancers: new era of treatment.Medical oncology (Northwood, London, England) · 2014
    Review
  16. Article
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  20. Thyroid cancer: pathogenesis and targeted therapy.Therapeutic advances in endocrinology and metabolism · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tricia A Moo-YoungDepartment of Surgery, Washington University School of Medicine, St Louis, MO 63110, USA.
Amber L Traugott
Jeffrey F Moley
Washington University in St. Louis · US

Funding

YOGA FOR THE MANAGEMENT OF HIV-METABOLIC SYNDROMESM01RR000036 · NCRR · WASHINGTON UNIVERSITY · PI NEWCOMER, JOHN W. · 1985 to 2007
$25.4M
NCRR NIH HHS M01 RR000036
6 · The paper itself

Abstract

Medullary thyroid cancer (MTC) accounts for 5% to 10% of all thyroid cancers. The high frequency of familial cases mandates screening and genetic testing. The aggressiveness and age of onset of familial MTC differs depending on the specific genetic mutation, and this should determine the timing and extent of surgery. Sporadic MTC can present at any age, and it is usually associated with a palpable mass and the presence of nodal metastases. Surgery is standard treatment for any patient presenting with resectable MTC. Further studies are needed to investigate the role of radiation therapy in the palliation and local control of postresection and advanced-stage MTC. New systemic therapies for metastatic disease are being investigated. Targeted molecular therapies, based on knowledge of the pathways affected by RET mutations, are being tested in multiple clinical trials.

Indexed as

Biomarkers, TumorCarcinoma, MedullaryCombined Modality TherapyDiagnosis, DifferentialDiagnostic ImagingGenetic Predisposition to DiseaseGenotypeHumansMultiple Endocrine Neoplasia Type 2aMultiple Endocrine Neoplasia Type 2bPhenotypePrognosisThyroid NeoplasmsBiomarkers, Tumor

Identifiers

PMID19836492
PMCPMC4768871
OpenAlexW2006046576

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.