ReviewBehavioural brain research2010
Zebrafish antipredatory responses: a future for translational research?
Review in Behavioural brain research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 2 syntheses or guidelines pooled it, 192 citations in OpenAlex.
- Pooled it
- Social Preference Tests in Zebrafish: A Systematic Review.Frontiers in veterinary science · 2020Pooled it
- Studying the Stress, Gene Expression, and Behavioral Changes Induced by Diazepam and Sertraline in a Zebrafish Model.Journal of applied toxicology : JAT · 2026Article
- A Standardized Unpredictable Chronic Stress Protocol for Adult Zebrafish.Current protocols · 2026Article
- How to Make Your Fish Work for You: Tips from Ethology and Ecology for Finding Appropriate Unconditioned Stimuli for Learning Studies withAnimals : an open access journal from MDPI · 2026Article
- Ethanol-Withanolides Interactions: Compound-Specific Effects on Zebrafish Larvae Locomotor Behavior and GABAA Receptor Subunit Expression.International journal of molecular sciences · 2025Article
- Does Personality Modulate the Sensitivity to Contaminants? A Case Study with Cadmium and Caffeine.Toxics · 2025Article
- Social stimuli impact behavioral responses to caffeine in the zebrafish.Scientific reports · 2024Article
- Background predation risk induces anxiety-like behaviour and predator neophobia in zebrafish.Animal cognition · 2024Article
- Aging in zebrafish is associated with reduced locomotor activity and strain dependent changes in bottom dwelling and thigmotaxis.PloS one · 2024Article
- Acute Administration of Ethanol and of a D1-Receptor Antagonist Affects the Behavior and Neurochemistry of Adult Zebrafish.Biomedicines · 2022Article
- Disease Modeling of Rare Neurological Disorders in Zebrafish.International journal of molecular sciences · 2022Review
- Behavioral Effects of Buspirone in Juvenile Zebrafish of Two Different Genetic Backgrounds.Toxics · 2022Article
- The effect of fish density and tank size on the behavior of adult zebrafish: A systematic analysis.Frontiers in behavioral neuroscience · 2022Article
- Zebrafish as an Animal Model for Testing Agents with Antidepressant Potential.Life (Basel, Switzerland) · 2021Review
- Stressor controllability modulates the stress response in fish.BMC neuroscience · 2021Article
- Hydrangeae Dulcis Folium Attenuates Physical Stress by Supressing ACTH-Induced Cortisol in Zebrafish.Chinese journal of integrative medicine · 2020Article
- Design and development of a robotic predator as a stimulus in conditioned place aversion for the study of the effect of ethanol and citalopram in zebrafish.Behavioural brain research · 2020Article
- Contextual fear learning and memory differ between stress coping styles in zebrafish.Scientific reports · 2019Article
- Nonlinear mixed-modelling discriminates the effect of chemicals and their mixtures on zebrafish behavior.Scientific reports · 2018Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Human neuropsychiatric conditions associated with abnormally exaggerated or misdirected fear (anxiety disorders and phobias) still represent a large unmet medical need because the biological mechanisms underlying these diseases are not well understood. Animal models have been proposed to facilitate this research. Here I review the literature with a focus on zebrafish, an upcoming laboratory organism in behavioral brain research. I argue that abnormal human fear responses are likely the result of the malfunction of neurobiological mechanisms (brain areas, circuits and/or molecular mechanisms) that originally evolved to support avoidance of predators or other harm in nature. I also argue that the understanding of the normal as well as pathological functioning of such mechanisms may be best achieved if one utilizes naturalistic experimental approaches. In case of laboratory model organisms, this may entail presenting stimuli associated with predators and measuring species-specific antipredatory responses. Although zebrafish is a relatively new subject of such inquiry, I review the recently rapidly increasing number of zebrafish studies in this area, and conclude that zebrafish is a promising research tool for the analysis of the neurobiology and genetics of vertebrate fear responses.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.