Evidence map›Paper›PMID 19834959›Full record

ArticleCancer2009

Finding what is not there: unwarranted claims of an effect of psychosocial intervention on recurrence and survival.

Michael E Stefanek, Steven C Palmer, Brett D Thombs, James C Coyne

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cancer, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Schwann cells: a new player in the tumor microenvironment.Cancer immunology, immunotherapy : CII · 2017
    Review
  4. Review
  5. Affective science perspectives on cancer control: strategically crafting a mutually beneficial research agenda.Perspectives on psychological science : a journal of the Association for Psychological Science · 2015
    Article
  6. Psychosocial care in cancer.Current psychiatry reports · 2012
    Review
  7. Host factors and cancer progression: biobehavioral signaling pathways and interventions.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2010
    Review
  8. Positive psychology in cancer care: bad science, exaggerated claims, and unproven medicine.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2010
    Article
  9. Positive psychology in cancer care: a story line resistant to evidence.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2010
    Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Michael E StefanekAmerican Cancer Society, Behavioral Research Center, Atlanta, Georgia 30303, USA. mstefanek@bellsouth.net
Steven C Palmer
Brett D Thombs
James C Coyne

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a recently published randomized trial, Andersen et al. claimed to observe a reduced risk of recurrence and improved survival among women with early stage breast cancer who were assigned to a psychological intervention versus an assessment-only group. Anderson et al. concluded that "psychological intervention, as delivered and studied here, can improve survival." The current commentary challenges that conclusion on methodological and statistical grounds, noting that the study by Andersen et al. was not designed to assess survival and used methods that capitalized on chance, making it highly unlikely that their claims could be replicated. No other study designed to assess whether psychosocial intervention provides a survival benefit for cancer patients has ever demonstrated such an effect; and, currently, there is no support for the hypothesis that survival benefits can be attributed to psychosocial intervention. The authors of this commentary argue that much needs to be learned at the more basic biobehavioral level about the impact of stress or psychological factors on tumor biology before even considering whether large clinical trials are warranted. In addition, making the claim that psychological interventions improve survival is not evidence-based, is potentially harmful, and detracts from the potential significant benefits of psychological interventions related to quality of life.

Indexed as

Clinical Trials as TopicPsychotherapyResearch DesignBreast NeoplasmsFemaleHumansNeoplasm Recurrence, LocalSocioenvironmental TherapyStress, PsychologicalSurvival Rate

Identifiers

PMID19834959

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.