COLD-PCR finds hot application in mutation analysis.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

9 citing papers in PubMed.

1. High-resolution melting (HRM) re-analysis of a polyposis patients cohort reveals previously undetected heterozygous and mosaic APC gene mutations.Familial cancer · 2015
   Article
2. Single-tube, highly parallel mutation enrichment in cancer gene panels by use of temperature-tolerant COLD-PCR.Clinical chemistry · 2015
   Article
3. Detection of hepatitis B virus genotypic resistance mutations by coamplification at lower denaturation temperature-PCR coupled with sanger sequencing.Journal of clinical microbiology · 2014
   Article
4. Targeted next-generation sequencing at copy-number breakpoints for personalized analysis of rearranged ends in solid tumors.PloS one · 2014
   Article
5. Enrichment of mutations in multiple DNA sequences using COLD-PCR in emulsion.PloS one · 2012
   Article
6. Multiplex amplification coupled with COLD-PCR and high resolution melting enables identification of low-abundance mutations in cancer samples with low DNA content.The Journal of molecular diagnostics : JMD · 2011
   Article
7. Ice-COLD-PCR enables rapid amplification and robust enrichment for low-abundance unknown DNA mutations.Nucleic acids research · 2011
   Article
8. Screening for EGFR and KRAS mutations in endobronchial ultrasound derived transbronchial needle aspirates in non-small cell lung cancer using COLD-PCR.PloS one · 2011
   Article
9. COLD-PCR enhanced melting curve analysis improves diagnostic accuracy for KRAS mutations in colorectal carcinoma.BMC clinical pathology · 2010
   Article

Corrections and comments

• Comment on
  COLD-PCR-enhanced high-resolution melting enables rapid and selective identification of low-level unknown mutations.2009

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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