Evidence map›Paper›PMID 19833544›Full record

ReviewCurrent opinion in chemical biology2009

Recent progress in chemical and chemoenzymatic synthesis of carbohydrates.

Saddam Muthana, Hongzhi Cao, Xi Chen

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in chemical biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 133 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Microbial Production of Human Milk Oligosaccharides.Molecules (Basel, Switzerland) · 2023
    Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Electrochemical Bromination of Glycals.Frontiers in chemistry · 2021
    Article
  13. Synthetic Carbohydrate Chemistry and Translational Medicine.The Journal of organic chemistry · 2020
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Machine-Driven Enzymatic Oligosaccharide Synthesis by Using a Peptide Synthesizer.Angewandte Chemie (International ed. in English) · 2018
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Saddam MuthanaDepartment of Chemistry, One Shields Avenue, University of California, Davis, CA 95616, United States.
Hongzhi Cao
Xi Chen
University of California, Davis · US

Funding

Studies of Naturally Occurring Structurally Modified CarbohydratesR01GM076360 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEN, XI · 2006 to 2010
$1.9M
NIGMS NIH HHS GM076360NIGMS NIH HHS R01 GM076360
6 · The paper itself

Abstract

The important roles that carbohydrates play in biological processes and their potential application in diagnosis, therapeutics, and vaccine development have made them attractive synthetic targets. Despite ongoing challenges, tremendous progresses have been made in recent years for the synthesis of carbohydrates. The chemical glycosylation methods have become more sophisticated and the synthesis of oligosaccharides has become more predictable. Simplified one-pot glycosylation strategy and automated synthesis are increasingly used to obtain biologically important glycans. On the other hand, chemoenzymatic synthesis continues to be a powerful alternative for obtaining complex carbohydrates. This review highlights recent progress in chemical and chemoenzymatic synthesis of carbohydrates with a particular focus on the methods developed for the synthesis of oligosaccharides, polysaccharides, glycolipids, and glycosylated natural products.

Indexed as

Biological ProductsCarbohydratesEnzymesGlycolipidsGlycoside HydrolasesGlycosylationHumansPolysaccharidesBiological ProductsCarbohydratesEnzymesGlycolipidsGlycoside HydrolasesPolysaccharides

Identifiers

PMID19833544
PMCPMC3097241
OpenAlexW2016330877

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.