ArticleMolecular biology reports2010
Overexpression of PgDREB2A transcription factor enhances abiotic stress tolerance and activates downstream stress-responsive genes.
Article in Molecular biology reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
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Who cites it
72 citing papers in PubMed, 188 citations in OpenAlex.
- Laying the blueprint of abiotic stress tolerance: an analysis on the complexities of the stress matrix.Plant signaling & behavior · 2026Review
- Genome-wide association study identifies candidate genes for agronomic traits under heat- and combined recurrent drought-and heat-stress in wheat.Scientific reports · 2026Article
- Transcription factor HvDREB4.1 and HvDREB4.2 from Hulless barley enhance tolerance to drought and salt stress in transgenic Arabidopsis thaliana.BMC plant biology · 2026Article
- Unveiling the role of CtDREB1B from safflower: enhancing plant resistance to drought and salt.BMC plant biology · 2026Article
- BPM Proteins Modulate Heat Stress Response inPlants (Basel, Switzerland) · 2025Article
- Drought Stress in Roses: A Comprehensive Review of Morphophysiological, Biochemical, and Molecular Responses.International journal of molecular sciences · 2025Review
- Review
- Genome-Wide Identification and Transcriptional Analysis ofInternational journal of molecular sciences · 2024Article
- The maize geneFrontiers in plant science · 2024Article
- A pervasive phosphorylation cascade modulation of plant transcription factors in response to abiotic stress.Planta · 2023Review
- Unleashing the Potential of EIL Transcription Factors in Enhancing Sweet Orange Resistance to Bacterial Pathologies: Genome-Wide Identification and Expression Profiling.International journal of molecular sciences · 2023Article
- Genome-wide transcriptional profiling provides clues to molecular mechanisms underlying cold tolerance in chickpea.Scientific reports · 2023Article
- Genome-Wide Analysis of thePlants (Basel, Switzerland) · 2023Article
- Genetic insights in pearl millet breeding in the genomic era: challenges and prospects.Plant biotechnology reports · 2023Review
- The NAC transcription factor MdNAC29 negatively regulates drought tolerance in apple.Frontiers in plant science · 2023Article
- Genome-wide identification and expression analysis ofPlant signaling & behavior · 2022Article
- Article
- A YSK-Type Dehydrin fromInternational journal of molecular sciences · 2022Article
- SugarcaneInternational journal of molecular sciences · 2022Article
- Expression of a Pennisetum glaucum gene DREB2A confers enhanced heat, drought and salinity tolerance in transgenic Arabidopsis.Molecular biology reports · 2022Article
12 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The DREB transcription factors comprise conserved ERF/AP2 DNA-binding domain, bind specifically to DRE/CRT motif and regulate abiotic stress mediated gene expression. In this study we show that PgDREB2A from Pennisetum glaucum is a powerful transcription factor to engineer multiple stress tolerance in tobacco plants. The PgDREB2A protein lacks any potential PEST sequence, which is known to act as a signal peptide for protein degradation. Therefore, the transgenic tobacco plants were raised using full-length cDNA without modification. The transgenics exhibited enhanced tolerance to both hyperionic and hyperosmotic stresses. At lower concentration of NaCl and mannitol, seed germination and seedling growth was similar in WT and transgenic, however at higher concentration germination in WT decreased significantly. D15 and D46 lines showed 4-fold higher germination percent at 200 mM NaCl. At 400 mM mannitol seed germination in WT was completely arrested, whereas in transgenic line it was more than 50%. Seedlings of D15 and D46 lines showed better growth like leaf area, root number, root length and fresh weight compared to wild type for both the stresses. The quantitative Real time PCR of transgenic showed higher expression of downstream genes NtERD10B, HSP70-3, Hsp18p, PLC3, AP2 domain TF, THT1, LTP1 and heat shock (NtHSF2) and pathogen-regulated (NtERF5) factors with different stress treatments.
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