Evidence map›Paper›PMID 19826799›Full record

ArticleEuropean journal of clinical pharmacology2010

Regional variation and adherence to guidelines for drug treatment of asthma.

Marianne Heibert Arnlind, Björn Wettermark, Mika Nokela, Paul Hjemdahl, Clas Rehnberg, Eva Wikström Jonsson

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Article in European journal of clinical pharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. Use of Natural Products in Asthma Treatment.Evidence-based complementary and alternative medicine : eCAM · 2020
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Asthma incidence in children growing up close to traffic: a registry-based birth cohort.Environmental health : a global access science source · 2013
    Article
  10. [Is "evidence-based medicine" followed by "confidence-based medicine"?].Medizinische Klinik (Munich, Germany : 1983) · 2010
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marianne Heibert ArnlindCentre for Allergy Research, Karolinska Institutet, Stockholm, Sweden. marianne.heibert.arnlind@ki.se
Björn Wettermark
Mika Nokela
Paul Hjemdahl
Clas Rehnberg
Eva Wikström Jonsson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo describe the utilization of antiasthmatic drugs in Sweden and to explore regional variations in drug utilization and adherence to guidelines for rational drug prescribing of antiasthmatics and their rationale.

methodsData on antiasthmatic drugs dispensed between July 2005 and December 2008 to all Swedish citizens aged between 18 and 44 years were obtained from the Swedish National Prescribed Drug Register. The period prevalence was determined by analyzing the number of users/1000 inhabitants, and the incidence by analyzing the number of new users after an 18-month drug-free wash-out period. Three drug-related indicators were used to assess the adherence to guidelines. All measures were analyzed by gender and region.

resultsA total of 161,000 patients were dispensed antiasthmatics in 2007, corresponding to a prevalence of 4 and 6% among men and women, respectively; the incidence rates were 2 and 3%, respectively. The total drug utilization and adherence to guidelines varied between regions. The total drug expenditures of antiastmatics were 258 million SEK (28 million euro), with fixed dose combinations accounting for 46% of the expenditure. No relation was found between models for allocating prescribing budgets or clear Drug and Therapeutics Committee recommendations and adherence to guidelines.

conclusionThere are large regional variations in the utilization of antiasthmatics between Swedish regions, with substantial room for improvement in the adherence to guidelines. New methods of influencing physician behavior may be needed in the future to enhance adherence.

Indexed as

Practice Guidelines as TopicAdolescentAdultAnti-Asthmatic AgentsAsthmaDrug CombinationsDrug UtilizationFees, PharmaceuticalFemaleGuideline AdherenceHumansMaleModels, StatisticalNational Health ProgramsPractice Patterns, Physicians'Prescription DrugsAnti-Asthmatic AgentsDrug CombinationsPrescription Drugs

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.