Evidence map›Paper›PMID 19826560›Full record

Trial reportInternational journal of environmental research and public health2009

A multicenter, randomized, open-labeled, parallel group trial of sildenafil in alcohol-associated erectile dysfunction: the impact on psychosocial outcomes.

Alexander M Ponizovsky, Lev Averbuch, Ira Radomislensky, Alexander Grinshpoon

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in International journal of environmental research and public health, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alexander M PonizovskyMental Health Services, Ministry of Health, Jerusalem 93591, Israel. alexander.ponizovsky@moh.health.gov.il
Lev Averbuch
Ira Radomislensky
Alexander Grinshpoon
Israel Ministry of Health · ILTirat Carmel Mental Health Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To examine the effect of sildenafil on erectile dysfunction (ED) and psychosocial outcomes in alcohol-dependent (AD) men, 108 men with these diagnoses were randomly assigned to either take sildenafil (50 mg) as add-on to standard treatment for AD, or the same treatment without sildenafil, for 12 weeks. Only 50 patients in sildenafil group and 51 in control group twice completed the International Index of Erectile Function (IIEF) and a battery of self-report questionnaires. IIEF scores and psychosocial functioning, self-esteem and support from friends improved only for sildenafil-treated patients (P < 0.001). The high effect sizes suggest that the observed benefits are unlikely to be a placebo effect, although their unspecific nature could not be ruled out. In men with ED associated with AD, sildenafil improves both ED and psychosocial outcomes. Further placebo-controlled clinical trial is warranted.

Indexed as

AdolescentAdultErectile DysfunctionEthanolHumansMaleMiddle AgedPhosphodiesterase InhibitorsPiperazinesPurinesSildenafil CitrateSulfonesTreatment OutcomeYoung AdultEthanolPhosphodiesterase InhibitorsPiperazinesPurinesSildenafil CitrateSulfonesalcohol dependencedepressionerectile dysfunctionfunctioningself-esteemsildenafilsocial support

Identifiers

PMID19826560
PMCPMC2760426
OpenAlexW1993091231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.