ReviewParasite immunology2009
Do helminths cause epilepsy?
Review in Parasite immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Updated evidence of the association between toxocariasis and epilepsy: Systematic review and meta-analysis.PLoS neglected tropical diseases · 2018Pooled it
- A systematic review of the frequency of neurocyticercosis with a focus on people with epilepsy.PLoS neglected tropical diseases · 2010Pooled it
- The potential relationship between Toxocara canis infection and epilepsy in a rat model.Parasitology research · 2025Article
- Epileptogenesis in Common Parasitic Infections.Current neurology and neuroscience reports · 2022Review
- Case-Control Study to Assess the Association between Epilepsy andMicroorganisms · 2021Article
- Immune System Investigation Using Parasitic Helminths.Annual review of immunology · 2021Review
- Article
- Article
- Incidence, Remission and Mortality of Convulsive Epilepsy in Rural Northeast South Africa.PloS one · 2015Article
- Frequency of Toxoplasma and Toxocara Sp. Antibodies in Epileptic Patients, in South Western Iran.Iranian journal of child neurology · 2015Article
- Prevalence and risk factors for active convulsive epilepsy in rural northeast South Africa.Epilepsy research · 2014Article
- Exposure to multiple parasites is associated with the prevalence of active convulsive epilepsy in sub-Saharan Africa.PLoS neglected tropical diseases · 2014Article
- Prevalence of active convulsive epilepsy in sub-Saharan Africa and associated risk factors: cross-sectional and case-control studies.The Lancet. Neurology · 2013Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 3 countries.
Funding
Abstract
Both helminthiases and epilepsy occur globally, and are particularly prevalent in developing regions of the world. Studies have suggested an association between epilepsy and helminth infection, but a causal relationship is not established in many helminths, except perhaps with neurocysticercosis. We review the available literature on the global burden of helminths, and the epidemiological evidence linking helminths to epilepsy. We discuss possible routes that helminths affect the central nervous system (CNS) of humans and the immunological response to helminth infection in the CNS, looking at possible mechanisms of epileptogenesis. Finally, we discuss the current gaps in knowledge about the interaction between helminths and epilepsy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.