Evidence map›Paper›PMID 19824943›Full record

ArticlePediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology2010

Exposure to traffic exhaust and night cough during early childhood: the CCAAPS birth cohort.

Heidi Sucharew, Patrick H Ryan, David Bernstein, Paul Succop, Gurjit K Khurana Hershey, James Lockey, Manuel Villareal, Tiina Reponen, Sergey Grinshpun, Grace LeMasters

Open access · greenAbstract read
In one paragraph

Article in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Clinical Practice Guideline: Immunotherapy for Inhalant Allergy.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024
    Guideline
  2. Guideline
  3. Executive Summary of Clinical Practice Guideline on Immunotherapy for Inhalant Allergy.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024
    Article
  4. Article
  5. Article
  6. Environmental triggers for chronic cough.Asia Pacific allergy · 2019
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Air pollution, epigenetics, and asthma.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2016
    Review
  13. Air pollution and allergic diseases.Current opinion in pediatrics · 2015
    Review
  14. Traffic pollution is associated with early childhood aeroallergen sensitization.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2015
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Heidi SucharewDepartment of Environmental Health, University of Cincinnati Medical Center, Cincinnati, OH 45267-0056, USA. sucharhj@email.uc.edu
Patrick H Ryan
David Bernstein
Paul Succop
Gurjit K Khurana Hershey
James Lockey
Manuel Villareal
Tiina Reponen
Sergey Grinshpun
Grace LeMasters
University of Cincinnati · USUniversity of Cincinnati Medical Center · USCincinnati Children's Hospital Medical Center · US

Funding

Molecular Epidemiology in Children's Environmental Health Training Program (MECEH)T32ES010957 · NIEHS · UNIVERSITY OF CINCINNATI · PI Kelly J Brunst · 2001 to 2026
$11.1M
Diesel, Allergens and Gene Interaction and Child AtopyR01ES011170 · NIEHS · UNIVERSITY OF CINCINNATI · PI LEMASTERS, GRACE · 2001 to 2009
$10.4M
NIEHS NIH HHS ES10957NIEHS NIH HHS ES11170NIEHS NIH HHS R01 ES011170NIEHS NIH HHS T32 ES010957
6 · The paper itself

Abstract

Though studies have investigated the association between air pollution and respiratory health outcomes in children, few have focused on night cough. The study objective was to simultaneously evaluate family factors (i.e., race, gender, maternal and paternal asthma, and breastfeeding), health (allergen sensitization and wheezing symptoms), home factors (dog, cat, mold, endotoxin, and dust mite), and other environmental exposures (traffic exhaust and second-hand tobacco smoke) for associations with recurrent dry night cough (RNC) during early childhood. A structural equation model with repeat measures was developed assessing RNC at ages one, two, and three. The prevalence of RNC was relatively large and similar at ages, one, two, and three at 21.6%, 17.3%, and 21.1%, respectively. Children exposed to the highest tertile of traffic exhaust had an estimated 45% increase in risk of RNC compared with children less exposed (adjusted OR 1.45, 95% CI: 1.09, 1.94). Also, wheezing was associated with a 76% higher risk of RNC (adjusted OR 1.76, 95% CI: 1.36, 2.26). A protective trend for breastfeeding was found with a 27% reduction in risk associated with breastfeeding (adjusted OR 0.73, 95% CI: 0.53, 1.01). No other factors were significant. These results suggest that traffic exhaust exposure may be a risk factor for night cough in young children.

Indexed as

Environmental ExposureAir PollutantsAnimalsAnimals, DomesticAsthmaBreast FeedingCatsChild, PreschoolCohort StudiesCoughDogsEndotoxinsFemaleFungiHumansInfantAir PollutantsEndotoxinsVehicle Emissions

Identifiers

PMID19824943
PMCPMC11610241
OpenAlexW2036016621

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.