Evidence map›Paper›PMID 19822569›Full record

ArticleAmerican journal of epidemiology2009

Body size, recreational physical activity, and B-cell non-Hodgkin lymphoma risk among women in the California teachers study.

Yani Lu, Jennifer Prescott, Jane Sullivan-Halley, Katherine D Henderson, Huiyan Ma, Ellen T Chang, Christina A Clarke, Pamela L Horn-Ross, Giske Ursin, Leslie Bernstein

Open access · bronzeAbstract read
In one paragraph

Article in American journal of epidemiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Physical Activity in Cancer Prevention and Survival: A Systematic Review.Medicine and science in sports and exercise · 2019
    Pooled it
  4. Pooled it
  5. Article
  6. Review
  7. Article
  8. Non-Hodgkin Lymphoma, Body Mass Index, and Cytokine Polymorphisms: A Pooled Analysis from the InterLymph Consortium.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Anthropometric characteristics and multiple myeloma risk.Epidemiology (Cambridge, Mass.) · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yani LuDivision of Cancer Etiology, Department of Population Science, City of Hope National Medical Center, Duarte, California 91010, USA. yalu@coh.org
Jennifer Prescott
Jane Sullivan-Halley
Katherine D Henderson
Huiyan Ma
Ellen T Chang
Christina A Clarke
Pamela L Horn-Ross
Giske Ursin
Leslie Bernstein
City Of Hope National Medical Center · US

Funding

CALIFORNIA TEACHERS STUDYR01CA077398 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BERNSTEIN, LESLIE · 1998 to 2014
$29.7M
Research and Mentoring on Energetic Factors and Cancer: Established InvestigatorK05CA136967 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI BERNSTEIN, LESLIE · 2009 to 2013
$684k
NCI NIH HHS K05 CA136967NCI NIH HHS N01 PC035136NCI NIH HHS N01 PC035139NCI NIH HHS N01-PC-35136NCI NIH HHS N01-PC-35139NCI NIH HHS N02 PC015105NCI NIH HHS R01 CA077398NCI NIH HHS R01 CA77398PHS HHS U55/CCR921930-02
6 · The paper itself

Abstract

Nutritional status and physical activity are known to alter immune function, which may be relevant to lymphomagenesis. The authors examined body size measurements and recreational physical activity in relation to risk of B-cell non-Hodgkin lymphoma (NHL) in the prospective California Teachers Study. Between 1995 and 2007, 574 women were diagnosed with incident B-cell NHL among 121,216 eligible women aged 22-84 years at cohort entry. Multivariable-adjusted relative risks and 95% confidence intervals were estimated by fitting Cox proportional hazards models for all B-cell NHL combined and for the 3 most common subtypes: diffuse large B-cell lymphoma, follicular lymphoma, and B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma. Height was positively associated with risk of all B-cell NHLs (for >1.70 vs. 1.61-1.65 m, relative risk = 1.50, 95% confidence interval: 1.16, 1.96) and chronic lymphocytic leukemia/small lymphocytic lymphoma (relative risk = 1.93, 95% confidence interval: 1.09, 3.41). Weight and body mass index at age 18 years were positive predictors of B-cell NHL risk overall. These findings indicate that greater height, which may reflect genetics, early life immune function, infectious exposures, nutrition, or growth hormone levels, may play a role in NHL etiology. Adiposity at age 18 years may be more relevant to NHL etiology than that in later life.

Indexed as

Body SizeMotor ActivityNutritional StatusRecreationAdultAgedAged, 80 and overBody Mass IndexCaliforniaCohort StudiesConfidence IntervalsFemaleHumansLife StyleLymphoma, B-CellMiddle Aged

Identifiers

PMID19822569
PMCPMC2781760
OpenAlexW2161966450

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.