ArticleVirology journal2009
Recombination in West Nile Virus: minimal contribution to genomic diversity.
Article in Virology journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Phylogenetic insights into the transmission dynamics of arthropod-borne viruses.Nature reviews. Genetics · 2026Review
- Correlated substitutions reveal SARS-like coronaviruses recombine frequently with a diverse set of structured gene pools.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Review
- Discriminating arboviral species.The Journal of general virology · 2021Article
- Evolutionary Dynamics of the Lineage 2 West Nile Virus That Caused the Largest European Epidemic: Italy 2011-2018.Viruses · 2019Article
- Identification of a putative novel genotype 3/rabbit hepatitis E virus (HEV) recombinant.PloS one · 2018Article
- Revisiting Recombination Signal in the Tick-Borne Encephalitis Virus: A Simulation Approach.PloS one · 2016Article
- Article
- Topology of viral evolution.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Article
- Origin and characteristics of internal genes affect infectivity of the novel avian-origin influenza A (H7N9) virus.PloS one · 2013Article
- Cooperative interactions in the West Nile virus mutant swarm.BMC evolutionary biology · 2012Article
- Genome-wide networks of amino acid covariances are common among viruses.Journal of virology · 2012Article
- Analysis of the genomic homologous recombination in Theilovirus based on complete genomes.Virology journal · 2011Article
- Molecular evolution of West Nile virus in a northern temperate region: Connecticut, USA 1999-2008.Virology · 2011Article
- First complete genomic characterization of two tick-borne encephalitis virus isolates obtained from wild rodents in South Korea.Virus genes · 2011Article
- Stability of yellow fever virus under recombinatory pressure as compared with chikungunya virus.PloS one · 2011Article
- Article
- Recombination analysis reveals a double recombination event in hepatitis E virus.Virology journal · 2010Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Recombination is known to play a role in the ability of various viruses to acquire sequence diversity. We consequently examined all available West Nile virus (WNV) whole genome sequences both phylogenetically and with a variety of computational recombination detection algorithms. We found that the number of distinct lineages present on a phylogenetic tree reconstruction to be identical to the 6 previously reported. Statistically-significant evidence for recombination was only observed in one whole genome sequence. This recombination event was within the NS5 polymerase coding region. All three viruses contributing to the recombination event were originally isolated in Africa at various times, with the major parent (SPU116_89_B), minor parent (KN3829), and recombinant sequence (AnMg798) belonging to WNV taxonomic lineages 2, 1a, and 2 respectively. This one isolated recombinant genome was out of a total of 154 sequences analyzed. It therefore does not seem likely that recombination contributes in any significant manner to the overall sequence variation within the WNV genome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.