ArticleMycoses2011
Incidence and predictors of invasive candidiasis associated with candidaemia in children.
Article in Mycoses, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Prevalence of Ocular Candidiasis and Candida Endophthalmitis in Patients With Candidemia: A Systematic Review and Meta-Analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Pooled it
- Safety of fluconazole in paediatrics: a systematic review.European journal of clinical pharmacology · 2013Pooled it
- Do Patients With Candidemia Need an Ophthalmologic Examination?Open forum infectious diseases · 2024Article
- Adjunctive Diagnostic Studies Completed Following Detection of Candidemia in Children: Secondary Analysis of Observed Practice From a Multicenter Cohort Study Conducted by the Pediatric Fungal Network.Journal of the Pediatric Infectious Diseases Society · 2023Article
- Epidemiology and associated risk factors for candidemia in a Canadian tertiary paediatric hospital: An 11-year review.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2023Article
- Diagnosis and Treatment of Invasive Candidiasis.Antibiotics (Basel, Switzerland) · 2022Review
- Emerging Prospects for Combating Fungal Infections by Targeting Phosphatidylinositol Transfer Proteins.International journal of molecular sciences · 2021Review
- The utility of abdominal ultrasonography in the diagnosis of fungal infections in children: a narrative review.Journal of medical radiation sciences · 2021Review
- Review
- How We Treat Fever and Hypotension in Pediatric Hematopoietic Cell Transplant Patients.Frontiers in oncology · 2020Review
- Global and Multi-National Prevalence of Fungal Diseases-Estimate Precision.Journal of fungi (Basel, Switzerland) · 2017Review
- Improved detection of deeply invasive candidiasis with DNA aptamers specific binding to (1→3)-β-D-glucans from Candida albicans.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016Article
- Review
- Ocular manifestations of candidemia in children.The Pediatric infectious disease journal · 2013Article
- Neonatal intensive care unit candidemia: epidemiology, risk factors, outcome, and critical review of published case series.Mycopathologia · 2012Article
- Fungemia caused by Candida species in a children's public hospital in the city of São Paulo, Brazil: study in the period 2007-2010.Revista do Instituto de Medicina Tropical de Sao PauloArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Risk factors for invasive candidiasis in children with candidaemia are poorly defined. We performed a retrospective cohort study of all children with candidaemia at our tertiary children's hospital from 2000 to 2006. Invasive candidiasis was diagnosed by review of the medical record and standardised EORTC/MSG criteria. A variety of risk factors for invasive candidiasis were explored. Of 194 episodes of candidaemia in the microbiology laboratory database, 180 clinical records were available. Evaluation for invasive candidiasis consisted of 174 (97%) echocardiograms, 167 (93%) dilated ophthalmological examinations, 136 (76%) chest CT scans and 108 (60%) abdominal ultrasounds (complete, hepatosplenic or renal). Of the 180 patients, 15 (8%) were identified with invasive candidiasis (4 proven, 1 probable, 10 possible). Prematurity <32 weeks (P < 0.01), an underlying immunocompromising disorder (P < 0.01), and ≥2 days of candidaemia (P = 0.05) were significantly associated with invasive candidiasis. Invasive candidiasis, especially proven or probable, in the setting of candidaemia was not common in our hospital, but premature infants and immunocompromised children were at significantly higher risk. Based on our findings, extensive imaging and examination by an ophthalmologist were particularly low-yield for invasive candidiasis in immunocompetent children beyond infancy.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.