Evidence map›Paper›PMID 19821354›Full record

SynthesisThe Cochrane database of systematic reviews2009

Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy.

Stephen G Schwartz, Harry W Flynn, Wen-Hsiang Lee, Elizabeth Ssemanda, Ann-Margret Ervin

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Sexual quality of life after gynaecological cancer: what young women want.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Management of recurrent rhegmatogenous retinal detachment.Indian journal of ophthalmology · 2018
    Review
  10. Article
  11. Article
  12. Heavy silicone oil and intraocular inflammation.BioMed research international · 2014
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Stephen G SchwartzBascom Palmer Eye Institute, University of Miami Miller School of Medicine, 311 9th Street North, #100, Naples, USA, FL 34102.
Harry W Flynn
Wen-Hsiang Lee
Elizabeth Ssemanda
Ann-Margret Ervin
Johns Hopkins University · USUniversity of Miami · US

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Dmitry V Ivanov · 2004 to 2026
$12.2M
COCHRANE EYE AND VISION GROUP-COORDINATING RESOURCE CENTER-260021003N01EY021003 · NEI · JOHNS HOPKINS UNIVERSITY · PI DICKERSIN, KAY · 2006 to 2006
–
NEI NIH HHS N01 EY021003NEI NIH HHS P30 EY014801
6 · The paper itself

Abstract

backgroundRetinal detachment (RD) with proliferative vitreoretinopathy (PVR) often requires surgery. During surgery, a tamponade agent is needed to reduce the rate of recurrent retinal detachment.

objectivesThe objective of this review was to evaluate the benefits and adverse outcomes of surgery with various tamponade agents. SEARCH STRATEGY: We searched the Cochrane Controlled Register (CENTRAL), MEDLINE, EMBASE, Latin America and Carribbean Health Sciences (LILACS) and the UK Clinical Trials Gateway (UKCTG). There were no language or date restrictions in the search for trials. The electronic databases were last searched on 9 July 2009. SELECTION CRITERIA: We included randomized clinical trials comparing patients treated with various tamponade agents. DATA COLLECTION AND ANALYSIS: Two individuals screened the search results independently. One study with two trials was eligible for inclusion in the review. MAIN

resultsOne study with two trials was included in the review. The first trial randomized 151 eyes to receive either silicone oil or sulfur hexafluoride (SF(6)) gas tamponades; the second trial randomized 271 eyes to receive either silicone oil or perfluropropane (C(3)F(8)) gas tamponades. In patients with RD associated with PVR, pars plana vitrectomy and infusion of either silicone oil or perfluropropane gas appear comparable for a broad variety of cases. Sulfur hexafluoride gas was associated with worse anatomic and visual outcomes than either silicone oil or perfluropropane gas. AUTHORS'

conclusionsThe use of either C(3)F(8) or silicone oil appears reasonable for most patients with RD associated with PVR. Because there do not appear to be any major differences in outcomes between the two agents, the choice of a tamponade agent should be individualized for each patient.

Indexed as

FluorocarbonsHumansRandomized Controlled Trials as TopicRetinal DetachmentSecondary PreventionSilicone OilsSulfur HexafluorideVitreoretinopathy, ProliferativeFluorocarbonsperflutrenSilicone OilsSulfur Hexafluoride

Identifiers

PMID19821354
PMCPMC3729221
OpenAlexW4243883094

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.