ArticleMolecular biology reports2010
Association of the SDF1-3'A polymorphism with susceptibility to myocardial infarction in Chinese Han population.
Article in Molecular biology reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Lack of an Association between the SDF-1 rs1801157 Polymorphism and Coronary Heart Disease: A Meta-Analysis.Scientific reports · 2015Pooled it
- Variants in theOncotarget · 2017Article
- Article
- The SDF-1α3'A genetic variation is correlated with susceptibility of asthma in Iranian patients.BioMed research international · 2013Article
- Genetic variants of SDF-1 and CXCR4 genes in endometrial carcinoma.Molecular biology reports · 2012Article
- Touch of chemokines.Frontiers in immunology · 2012Article
- Relationship between surfactant protein A polymorphisms and allergic rhinitis in a Chinese Han population.Molecular biology reports · 2011Article
- Effect of genetic variants of chemokine receptors on the development of myocardial infarction in Turkish population.Molecular biology reports · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
SDF-1 has been demonstrated to be involved in the pathophysiology of atherosclerosis. This study was aimed to investigate whether the SDF1-3'A polymorphism (rs1801157) is associated to myocardial infarction (MI) in a sample of Chinese Han population. A total of 560 patients with MI and 532 controls were enrolled in the study. The SDF1-3'A polymorphism was determined by polymerase chain reaction -restriction fragment length polymorphism (PCR-RFLP) analysis. A significant difference in genotype distribution and allele frequency was observed between patients and controls (P = 0.003 and P = 0.001, respectively). The A allele carriers had a significantly reduced MI risk compared with the GG homozygotes (OR, 0.69; 95% CI, 0.52-0.92; adjusted P = 0.007) in a logistic regression model after controlling conventional risk factors. The present study showed a significant association between the SDF1-3'A polymorphism and MI in Chinese Han population.
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Registered trials
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