Evidence map›Paper›PMID 19820906›Full record

ReviewDer Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen2009

[Neoadjuvant therapy of adenocarcinomas of the upper gastrointestinal tract. Status of radiotherapy].

R Semrau, D Vallböhmer, A H Hölscher, R-P Müller

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. [Modern diagnostics and stage-oriented surgery: therapy of adenocarcinoma of the esophagogastric junction].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

R SemrauKlinik und Poliklinik für Strahlentherapie, Universität zu Köln, Köln. Robert.Semrau@uk-koeln.de
D Vallböhmer
A H Hölscher
R-P Müller
University of Cologne · DEKlinik und Poliklinik für Strahlentherapie und Radioonkologie · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiotherapy in combination with simultaneous chemotherapy can improve survival of advanced esophageal adenocarcinoma. The extent of histopathological tumor regression achieved by the therapy is a relevant prognostic factor for this tumor entity. Response evaluation after radiochemotherapy of esophageal carcinoma will rely more and more on molecular factors and will allow individualization of the therapy. New combinations with taxanes and irinotecan as well as EGF receptor antagonists need to be evaluated in phase III trials. Postoperative chemoradiation and perioperative chemotherapy are evaluated in gastric adenocarcinomas and show a survival advantage. Surgery techniques used in theses trials are not recommended in current clinical guidelines.

Indexed as

Neoadjuvant TherapyAdenocarcinomaCarcinoma, Squamous CellChemotherapy, AdjuvantCombined Modality TherapyDisease-Free SurvivalDose Fractionation, RadiationEsophageal NeoplasmsHumansLymphatic MetastasisNeoplasm StagingPrognosisRadiotherapy, AdjuvantRandomized Controlled Trials as TopicStomach Neoplasms

Identifiers

PMID19820906
OpenAlexW1605369377

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.