ArticlePlant signaling & behavior2009
Suppression of MKK5 reduces ozone-induced signal transmission to both MPK3 and MPK6 and confers increased ozone sensitivity in Arabidopsis thaliana.
Article in Plant signaling & behavior, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 19 citations in OpenAlex.
- Plant responses to gaseous pollutants, biochemical and transcriptomic insights.Frontiers in plant science · 2026Review
- Characteristics ofInternational journal of molecular sciences · 2021Article
- Monitoring of new coronavirus (SARS-CoV-2): Origin, transmission, and food preservation methods.Journal of food processing and preservation · 2021Review
- A review of redox signaling and the control of MAP kinase pathway in plants.Redox biology · 2017Review
- RhMKK9, a rose MAP KINASE KINASE gene, is involved in rehydration-triggered ethylene production in rose gynoecia.BMC plant biology · 2017Article
- Mitogen-activated protein kinase kinase 5 (MKK5)-mediated signalling cascade regulates expression of iron superoxide dismutase gene in Arabidopsis under salinity stress.Journal of experimental botany · 2015Article
- Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.Molecular & cellular proteomics : MCP · 2013Article
- Cotton GhMKK5 affects disease resistance, induces HR-like cell death, and reduces the tolerance to salt and drought stress in transgenic Nicotiana benthamiana.Journal of experimental botany · 2012Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Arabidopsis thaliana, ozone-induced signaling has been shown to involve the mitogen-activated protein kinases (MAPKs) MPK3 and MPK6. To identify a possible ozone-induced mitogen-activated protein kinase kinase (MAPKK) involved in the activation of these specific MAPKs, we employed RNA interference-(RNAi)-based suppression of MKK5, a known cognate MAPKK to both MPK3 and MPK6. When exposed to ozone, activation of both MPK3 and MPK6 was markedly reduced in the MKK5-suppressed plants compared to WT. Additionally, the MKK5-suppressed plants were found to be highly sensitive to ozone as determined by visible leaf damage concomitant with elevated levels of leaf-localised H(2)O(2). Taken together, our data suggest MKK5 functions both in ozone-induced activation of MPK3 and MPK6 and in integrating ROS homeostasis during ozone stress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.