ArticleThe Plant cell2009
Stage-specific regulation of Solanum lycopersicum leaf maturation by class 1 KNOTTED1-LIKE HOMEOBOX proteins.
Article in The Plant cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
87 citing papers in PubMed.
- New components in genetic regulation of age-dependent compound leaf architecture in pea.The New phytologist · 2026Article
- Progressive oxygenation of developing leaves directs morphogenesis.Science advances · 2026Article
- A two-step auxin-GA cross-talk regulates organ formation in tomato.Development (Cambridge, England) · 2026Article
- Ectopic cambia in wisteria vines are associated with the expression of conserved KNOX genes.Nature communications · 2026Article
- Homeodomain transcription factor regulation of leaf serrations in Arabidopsis thaliana.Journal of experimental botany · 2025Article
- The GhWL1-GhH1-GhGA2OX1 Transcriptional Module Regulates Cotton Leaf Morphology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Article
- Single-cell transcriptomic analysis of flowering regulation and vernalization in Chinese cabbage shoot apex.Horticulture research · 2024Article
- A novel tomato interspecific (Horticulture research · 2024Article
- Shaping leaves through TALE homeodomain transcription factors.Journal of experimental botany · 2024Review
- Genomic analysis of a spontaneous unifoliate mutant reveals gene candidates associated with compound leaf development in Vigna unguiculata [L] Walp.Scientific reports · 2024Article
- Rewiring of a KNOXI regulatory network mediated by UFO underlies the compound leaf development in Medicago truncatula.Nature communications · 2024Article
- Article
- Roles of very long-chain fatty acids in compound leaf patterning in Medicago truncatula.Plant physiology · 2023Article
- Diversity of tomato leaf form provides novel insights into breeding.Breeding science · 2023Article
- Genome-Wide Identification of Wheat KNOX Gene Family and Functional Characterization ofInternational journal of molecular sciences · 2022Article
- Article
- SHOOT MERISTEMLESS participates in the heterophylly of Hygrophila difformis (Acanthaceae).Plant physiology · 2022Article
- Co-option of the SHOOT MERISTEMLESS network regulates protocorm-like body development in Phalaenopsis aphrodite.Plant physiology · 2022Article
- Genome-wide characterization of the TALE homeodomain family and the KNOX-BLH interaction network in tomato.Plant molecular biology · 2022Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Class 1 KNOTTED1-LIKE HOMEOBOX (KNOXI) genes encode transcription factors that are expressed in the shoot apical meristem (SAM) and are essential for SAM maintenance. In some species with compound leaves, including tomato (Solanum lycopersicum), KNOXI genes are also expressed during leaf development and affect leaf morphology. To dissect the role of KNOXI proteins in leaf patterning, we expressed in tomato leaves a fusion of the tomato KNOXI gene Tkn2 with a sequence encoding a repressor domain, expected to repress common targets of tomato KNOXI proteins. This resulted in the formation of small, narrow, and simple leaves due to accelerated differentiation. Overexpression of the wild-type form of Tkn1 or Tkn2 in young leaves also resulted in narrow and simple leaves, but in this case, leaf development was blocked at the initiation stage. Expression of Tkn1 or Tkn2 during a series of spatial and temporal windows in leaf development identified leaf initiation and primary morphogenesis as specific developmental contexts at which the tomato leaf is responsive to KNOXI activity. Arabidopsis thaliana leaves responded to overexpression of Arabidopsis or tomato KNOXI genes during the morphogenetic stage but were largely insensitive to their overexpression during leaf initiation. These results imply that KNOXI proteins act at specific stages within the compound-leaf development program to delay maturation and enable leaflet formation, rather than set the compound leaf route.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.