ArticleCurrent biology : CB2009
A ROP GTPase signaling pathway controls cortical microtubule ordering and cell expansion in Arabidopsis.
Article in Current biology : CB, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
111 citing papers in PubMed, 249 citations in OpenAlex.
- Independent roles of Arp2/3 complex and RIC4 protein in the control of epidermal cell shape.Planta · 2026Article
- Cytoskeletal control of development and environmental adaptation in plants.Science China. Life sciences · 2026Review
- The evolution of RHO of plant (ROP) proteins and their morphogenetic functions.The New phytologist · 2025Review
- Barley resistance and susceptibility to fungal cell entry involve the interplay of ROP signaling with phosphatidylinositol-monophosphates.The Plant journal : for cell and molecular biology · 2025Article
- The Turing heritage for plant biology: all spots and stripes?Quantitative plant biology · 2025Article
- Polar localization and local translation of RHO-RELATED PROTEIN FROM PLANTS2 mRNAs promote root hair growth in Arabidopsis.The Plant cell · 2024Article
- Hierarchical global and local auxin signals coordinate cellular interdigitation inbioRxiv : the preprint server for biology · 2024Article
- Rho of Plants patterning: linking mathematical models and molecular diversity.Journal of experimental botany · 2024Review
- Microtubule-associated phase separation of MIDD1 tunes cell wall spacing in xylem vessels in Arabidopsis thaliana.Nature plants · 2024Article
- Auxin as an architect of the pectin matrix.Journal of experimental botany · 2023Review
- Abscisic Acid Inhibits Cortical Microtubules Reorganization and Enhances Ultraviolet-B Tolerance inGenes · 2023Article
- The receptor kinase FERONIA regulates phosphatidylserine localization at the cell surface to modulate ROP signaling.Science advances · 2023Article
- Integrated analysis of biparental and natural populations reveals CRIB domain-containing protein underlying seed coat crack trait in watermelon.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Barley RIC157, a potential RACB scaffold protein, is involved in susceptibility to powdery mildew.Plant molecular biology · 2023Article
- Signaling network controlling ROP-mediated tip growth in Arabidopsis and beyond.Plant communications · 2023Review
- Mechano-chemical regulation of complex cell shape formation: Epidermal pavement cells-A case study.Quantitative plant biology · 2023Review
- ROP signaling regulates spatial pattern of cell division and specification of meristem notch.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Molecular Mechanisms of Diverse Auxin Responses during Plant Growth and Development.International journal of molecular sciences · 2022Review
- Current Understanding of the Genetics and Molecular Mechanisms Regulating Wood Formation in Plants.Genes · 2022Review
- Cell biology of the leaf epidermis: Fate specification, morphogenesis, and coordination.The Plant cell · 2022Review
51 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Cortical microtubules (MTs) participate in the spatial control of cell expansion and division that is required for plant growth and morphogenesis. Well-ordered transverse cortical MTs promote cell elongation and restrict radial cell expansion. The molecular mechanism controlling their ordering is poorly understood. We report the first known signaling pathway that promotes the organization of cortical MTs into parallel arrays oriented perpendicular to the axis of cell elongation in plants. Well-ordered MTs locally restrict cell expansion to promote indentation formation in the jigsaw-puzzle-shaped pavement cells of Arabidopsis leaves. Deleting ROP6, a Rho-family GTPase, randomized cortical MTs and released the localized restriction of cell expansion, whereas ROP6 overexpression enhanced MT ordering, turning the jigsaw-puzzle appearance of cells into a cylindrical shape. ROP6 directly binds and activates MT-associated RIC1 to achieve the MT ordering. The ROP6-RIC1 pathway also affects MT ordering of hypocotyl cells, showing a broad role for this pathway in the spatial regulation of cell expansion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.