ArticleCanadian journal of gastroenterology = Journal canadien de gastroenterologie2009
Longstanding eosinophilic gastroenteritis of more than 20 years.
Article in Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Eosinophilic Jejunitis Presenting as Intractable Vomiting, Persistent Leukocytosis, and Ascites in a Young Adult Patient.Journal of medical cases · 2024Article
- Eosinophilic enteritis in a case of cystic fibrosis: an elusive diagnosis with an elementary cure.BMJ case reports · 2023Article
- Eosinophilic gastroenteritis - a manifestation of an allergic disease in the gastrointestinal tract? Part 2. Treatment.Przeglad gastroenterologiczny · 2023Review
- Eosinophilic Gastritis/Gastroenteritis.Current gastroenterology reports · 2021Review
- Eosinophilic gastroenteritis: diagnosis and clinical perspectives.Clinical and experimental gastroenterology · 2019Review
- Massive hemorrhagic ascites: A rare presentation of eosinophilic gastroenteritis.World journal of clinical cases · 2018Article
- Eosinophilic gastroenteritis: Approach to diagnosis and management.World journal of gastrointestinal pharmacology and therapeutics · 2016Review
- A Case of Eosinophilic Gastroenteritis with Ascites.Case reports in medicine · 2015Article
- Eosinophilic gastroenteritis and related eosinophilic disorders.Gastroenterology clinics of North America · 2014Article
- Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Eosinophilic gastroenteritis (EGE) is an eosinophil-predominant inflammatory process that may be detected in endoscopic gastric or intestinal biopsies. The long-term natural history and effects of EGE treatment are not known. A 44-year-old man with abdominal pain was treated with oral ketotifen and followed for more than 20 years. Ketotifen provided symptomatic benefit, with prompt clinical relapse if the drug was discontinued. However, despite the use of ketotifen, the endoscopic abnormalities persisted and appeared to progress. Gastric body and antral mucosal folds appeared thickened, erythematous and friable, with minimal erosive change. Later, even during long asymptomatic periods suggesting clinical 'remission', inflammatory polypoid change, previously described in children with EGE, developed with mucosal 'pock-marking' and apparent scarring. Ketotifen treatment does not appear to prohibit or reverse the inflammatory process in the gastric mucosa in EGE, although long-term effects of steroids may be avoided. In the future, treatment of EGE may involve monoclonal antibody agents that target the specific biological effects of the eosinophil, apparently central to this unusual inflammatory process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.