ReviewInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2009
Neonatal resuscitation in low-resource settings: what, who, and how to overcome challenges to scale up?
Review in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 165 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
165 citing papers in PubMed, 9 syntheses or guidelines pooled it, 353 citations in OpenAlex.
- Effectiveness of Neonatal Resuscitation Training Programs, Implementation, and Scale-Up in Low- and Middle-Income Countries.Neonatology · 2025Pooled it
- Neonatal resuscitation in Eastern Africa: health care providers' level of knowledge and its determinants. A systematic review and meta-analysis.Global health action · 2024Pooled it
- Effect of the Helping Babies Breathe Program on Newborn Outcomes: Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Digital tracheal intubation and finger palpation to confirm endotracheal tube tip position in neonates: A systematic review and meta-analysis.Pediatric pulmonology · 2021Pooled it
- Does the Helping Babies Breathe Programme impact on neonatal resuscitation care practices? Results from systematic review and meta-analysis.Acta paediatrica (Oslo, Norway : 1992) · 2019Pooled it
- Pooled it
- Intrapartum-related neonatal encephalopathy incidence and impairment at regional and global levels for 2010 with trends from 1990.Pediatric research · 2013Pooled it
- Neonatal resuscitation and immediate newborn assessment and stimulation for the prevention of neonatal deaths: a systematic review, meta-analysis and Delphi estimation of mortality effect.BMC public health · 2011Pooled it
- 60 Million non-facility births: who can deliver in community settings to reduce intrapartum-related deaths?International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2009Pooled it
- An innovative, digital approach to training district health care providers on essential newborn care skills: findings from a pilot cluster-randomised trial in Lao People's Democratic Republic.Journal of global health · 2025Trial
- Umbilical cord milking in nonvigorous infants: a cluster-randomized crossover trial.American journal of obstetrics and gynecology · 2023Trial
- Evaluation of Adaptive Feedback in a Smartphone-Based Game on Health Care Providers' Learning Gain: Randomized Controlled Trial.Journal of medical Internet research · 2020Trial
- Accelerating newborn survival in Ghana through a low-dose, high-frequency health worker training approach: a cluster randomized trial.BMC pregnancy and childbirth · 2018Trial
- Trial
- Caffeine to improve breathing effort of preterm infants at birth: a randomized controlled trial.Pediatric research · 2017Trial
- Impact Evaluation of PRONTO Mexico: A Simulation-Based Program in Obstetric and Neonatal Emergencies and Team Training.Simulation in healthcare : journal of the Society for Simulation in Healthcare · 2016Trial
- Implementing a simplified neonatal resuscitation protocol-helping babies breathe at birth (HBB) - at a tertiary level hospital in Nepal for an increased perinatal survival.BMC pediatrics · 2012Trial
- Training Zambian traditional birth attendants to reduce neonatal mortality in the Lufwanyama Neonatal Survival Project (LUNESP).International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2012Trial
- Effect of training traditional birth attendants on neonatal mortality (Lufwanyama Neonatal Survival Project): randomised controlled study.BMJ (Clinical research ed.) · 2011Trial
- Trial
105 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 7 institutions in 4 countries.
Funding
Abstract
backgroundEach year approximately 10 million babies do not breathe immediately at birth, of which about 6 million require basic neonatal resuscitation. The major burden is in low-income settings, where health system capacity to provide neonatal resuscitation is inadequate.
objectiveTo systematically review the evidence for neonatal resuscitation content, training and competency, equipment and supplies, cost, and key program considerations, specifically for resource-constrained settings.
resultsEvidence from several observational studies shows that facility-based basic neonatal resuscitation may avert 30% of intrapartum-related neonatal deaths. Very few babies require advanced resuscitation (endotracheal intubation and drugs) and these newborns may not survive without ongoing ventilation; hence, advanced neonatal resuscitation is not a priority in settings without neonatal intensive care. Of the 60 million nonfacility births, most do not have access to resuscitation. Several trials have shown that a range of community health workers can perform neonatal resuscitation with an estimated effect of a 20% reduction in intrapartum-related neonatal deaths, based on expert opinion. Case studies illustrate key considerations for scale up.
conclusionBasic resuscitation would substantially reduce intrapartum-related neonatal deaths. Where births occur in facilities, it is a priority to ensure that all birth attendants are competent in resuscitation. Strategies to address the gap for home births are urgently required. More data are required to determine the impact of neonatal resuscitation, particularly on long-term outcomes in low-income settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.