Evidence map›Paper›PMID 19814922›Full record

ReviewCurrent allergy and asthma reports2009

Neural control of airway inflammation.

Kirsten C Verhein, Allison D Fryer, David B Jacoby

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Airway Innervation and Plasticity in Asthma.Physiology (Bethesda, Md.) · 2019
    Review
  7. The Organophosphorus Pesticide Chlorpyrifos Induces Sex-Specific Airway Hyperreactivity in Adult Rats.Toxicological sciences : an official journal of the Society of Toxicology · 2018
    Article
  8. Article
  9. Article
  10. Brain-derived neurotrophic factor in the airways.Pharmacology & therapeutics · 2014
    Review
  11. Genome-wide association mapping of acute lung injury in neonatal inbred mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2014
    Article
  12. Airway smooth muscle in airway reactivity and remodeling: what have we learned?American journal of physiology. Lung cellular and molecular physiology · 2013
    Review
  13. Article
  14. Neurokinin-neurotrophin interactions in airway smooth muscle.American journal of physiology. Lung cellular and molecular physiology · 2011
    Article
  15. Neurotrophins in lung health and disease.Expert review of respiratory medicine · 2010
    Review
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kirsten C Verhein
Allison D Fryer
David B Jacoby
Oregon Health & Science University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abnormal neural function contributes to the pathogenesis of airway disease. In addition to affecting airway physiology, the nerves produce and release inflammatory mediators, contributing to the recruitment and activation of leukocytes. Activated inflammatory cells in turn affect the function of airway nerves, changing the production and release of neurotransmitters. Cross-talk between airway nerves and leukocytes helps to maintain chronic inflammation and accentuates neural control of the airways.

Indexed as

AnimalsAsthmaHumansInflammationInflammation MediatorsLungParasympathetic Nervous SystemPulmonary Disease, Chronic ObstructiveReceptors, AdrenergicReceptors, MuscarinicSympathetic Nervous SystemSynaptic TransmissionInflammation MediatorsReceptors, AdrenergicReceptors, Muscarinic

Identifiers

PMID19814922
OpenAlexW2156864229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.