ArticleAlimentary pharmacology & therapeutics2010
The assessment of regional gut transit times in healthy controls and patients with gastroparesis using wireless motility technology.
Article in Alimentary pharmacology & therapeutics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02573519 (Gastrointestinal Motility Among Diabetes Patients), which is not on this map. Cited by 60 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Gastrointestinal Motility Among Diabetes Patients
Who cites it
60 citing papers in PubMed.
- Transcutaneous vagal nerve stimulation for treating gastrointestinal symptoms in individuals with diabetes: a randomised, double-blind, sham-controlled, multicentre trial.Diabetologia · 2024Trial
- Prolonged lipopolysaccharide-induced illness elevates glucagon-like peptide-1 and suppresses peptide YY: A human-randomized cross-over trial.Physiological reports · 2022Trial
- Liraglutide accelerates colonic transit in people with type 1 diabetes and polyneuropathy: A randomised, double-blind, placebo-controlled trial.United European gastroenterology journal · 2020Trial
- Effects of Clozapine on the Gut: Cross-Sectional Study of Delayed Gastric Emptying and Small and Large Intestinal Dysmotility.CNS drugs · 2019Trial
- Type 1 diabetic patients with peripheral neuropathy have pan-enteric prolongation of gastrointestinal transit times and an altered caecal pH profile.Diabetologia · 2017Trial
- Blunting of Colon Contractions in Diabetics with Gastroparesis Quantified by Wireless Motility Capsule Methods.PloS one · 2015Trial
- Trial
- Diagnosis of Functional Dyspepsia and Novel Gastrointestinal Functional Assessments.Digestion · 2026Review
- Diabetic gastroenteropathy: Associations between gastrointestinal symptoms, motility, and extraintestinal autonomic measures.Neurogastroenterology and motility · 2026Article
- Prolonged Gastrointestinal Transit Times and Dysmotility in m.3243A>G Mitochondrial Disease.Neurogastroenterology and motility · 2025Article
- Panenteric Transit Times and Contractile Activity in Diabetic Gastroenteropathy.Journal of neurogastroenterology and motility · 2025Article
- Faecal microbiota transplantation for patients with diabetes type 1 and severe gastrointestinal neuropathy (FADIGAS): a randomised, double-blinded, placebo-controlled trial.EClinicalMedicine · 2025Article
- Whole Gut Motility Patterns in Patients with Chronic Nausea and Vomiting.Journal of clinical medicine · 2024Article
- Comparison of Gas-sensing Capsule With Wireless Motility Capsule in Motility Disorder Patients.Journal of neurogastroenterology and motility · 2024Article
- Imaging in Gastroparesis: Exploring Innovative Diagnostic Approaches, Symptoms, and Treatment.Life (Basel, Switzerland) · 2023Review
- Ten controversies in gastroparesis and a look to the future.Neurogastroenterology and motility · 2023Review
- Comparison of gastrointestinal landmarks using the gas-sensing capsule and wireless motility capsule.Alimentary pharmacology & therapeutics · 2022Article
- Gastrocolic Reflex Is Delayed and Diminished in Adults with Type 1 Diabetes.Digestive diseases and sciences · 2022Article
- Gastroparesis with concomitant gastrointestinal dysmotility is not a contraindication for per-oral pyloromyotomy (POP).Surgical endoscopy · 2022Article
- Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
backgroundWireless pH and pressure motility capsule (wireless motility capsule) technology provides a method to assess regional gastrointestinal transit times.
aimsTo analyse data from a multi-centre study of gastroparetic patients and healthy controls and to compare regional transit times measured by wireless motility capsule in healthy controls and gastroparetics (GP).
methodsA total of 66 healthy controls and 34 patients with GP (15 diabetic and 19 idiopathic) swallowed wireless motility capsule together with standardized meal (255 kcal). Gastric emptying time (GET), small bowel transit time (SBTT), colon transit time (CTT) and whole gut transit time (WGTT) were calculated using the wireless motility capsule.
resultsGastric emptying time, CTT and WGTT but not SBTT were significantly longer in GP than in controls. Eighteen percent of gastroparetic patients had delayed WGTT. Both diabetic and idiopathic aetiologies of gastroparetics had significantly slower WGTT (P < 0.0001) in addition to significantly slower GET than healthy controls. Diabetic gastroparetics additionally had significantly slower CTT than healthy controls (P = 0.0054).
conclusionsIn addition to assessing gastric emptying, regional transit times can be measured using wireless motility capsule. The prolongation of CTT in gastroparetic patients indicates that dysmotility beyond the stomach in GP is present, and it could be contributing to symptom presentation.
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