Evidence map›Paper›PMID 19811920›Full record

ReviewTrends in biochemical sciences2010

Glutaredoxins: roles in iron homeostasis.

Nicolas Rouhier, Jérémy Couturier, Michael K Johnson, Jean-Pierre Jacquot

Abstract readReview
In one paragraph

Review in Trends in biochemical sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Sulfur Administration in Fe-S Cluster Homeostasis.Antioxidants (Basel, Switzerland) · 2021
    Review
  13. Article
  14. The Role of GSH in Intracellular Iron Trafficking.International journal of molecular sciences · 2021
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicolas RouhierUnité Mixte de Recherches 1136 INRA Nancy University, Interactions Arbres Microorganismes, IFR 110 EFABA, Faculté des Sciences, Vandoeuvre Cedex, France. nrouhier@scbiol.uhp-nancy.fr
Jérémy Couturier
Michael K Johnson
Jean-Pierre Jacquot

Funding

Assembly of Biological Iron-Sulfur ClustersR01GM062524 · NIGMS · UNIVERSITY OF GEORGIA (UGA) · PI JOHNSON, MICHAEL K. · 2001 to 2012
$2.7M
Assembly and Repair of Biological Iron-Sulfur ClustersR37GM062524 · NIGMS · UNIVERSITY OF GEORGIA · PI JOHNSON, MICHAEL K. · 2014 to 2018
$1.7M
NIGMS NIH HHS GM62524NIGMS NIH HHS R01 GM062524NIGMS NIH HHS R37 GM062524
6 · The paper itself

Abstract

Glutaredoxins, proteins traditionally involved in redox reactions, are also required for iron-sulfur cluster assembly and haem biosynthesis. These new roles are probably related to the ability of some glutaredoxins to bind labile [2Fe-2S] clusters and to transfer them rapidly and efficiently to acceptor proteins. Recent results point to putative roles for glutaredoxins in the sensing of cellular iron and in iron-sulfur cluster biogenesis, either as scaffold proteins for the de novo synthesis of iron-sulfur clusters or as carrier proteins for the transfer of preformed iron-sulfur clusters. Based on prokaryote genome analysis and in vivo studies of iron regulation in yeast, we propose putative new roles and binding partners for glutaredoxins in the assembly of metalloproteins.

Indexed as

AnimalsGlutaredoxinsHemeHumansIronIron-Sulfur ProteinsPlantsGlutaredoxinsHemeIronIron-Sulfur Proteins

Identifiers

PMID19811920
PMCPMC2818164

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.