Evidence map›Paper›PMID 19810095›Full record

ArticleInternational journal of cancer2010

Salivary gland and nasopharyngeal cancers in individuals with acquired immunodeficiency syndrome in United States.

Fatma M Shebl, Kishor Bhatia, Eric A Engels

Open access · bronzeAbstract readLetter
In one paragraph

Article in International journal of cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Emerging and re-emerging infectious disease in otorhinolaryngology.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2018
    Review
  12. Article
  13. Faster Triage of Veterans With Head and Neck Cancer.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2016
    Article
  14. Article
  15. Article
  16. Early detection of nasopharyngeal carcinoma.International journal of otolaryngology · 2011
    Article
  17. Article
  18. Epidemiology of thymoma and associated malignancies.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Fatma M Shebl
Kishor Bhatia
Eric A Engels
National Cancer Institute · US

Funding

Infections, immunity, and inflammation in cancerZ01CP010150 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ENGELS, ERIC A · 2000 to 2008
$3.0M
Intramural NIH HHS Z01 CP010150Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

Individuals with acquired immunodeficiency syndrome (AIDS) manifest an increased risk of cancer, particularly cancers caused by oncogenic viruses. Because some salivary gland and nasopharyngeal cancers are associated with Epstein Barr virus, the impact of AIDS on these cancers needs further evaluation. We used linked U.S. AIDS and cancer registry data (N = 519,934 people with AIDS) to derive standardized incidence ratios (SIRs) comparing risk of salivary gland and nasopharyngeal cancers to the general population. For salivary gland cancers (N = 43 cases), individuals with AIDS had strongly elevated risks for lymphoepithelial carcinoma (SIR 39, 95% CI 16-81) and squamous cell carcinoma (SIR 4.9, 95% CI 2.5-8.6). Among nasopharyngeal cancers (N = 39 cases), risks were elevated for both keratinizing and nonkeratinizing carcinomas (SIR 2.4, 95% CI 1.5-3.7 and SIR 2.4, 95% CI 1.2-4.4, respectively). The elevated risks of salivary gland and nasopharyngeal cancers among people with AIDS suggest that immunosuppression and oncogenic viral infections are etiologically important.

Indexed as

Immunocompromised HostAcquired Immunodeficiency SyndromeAdolescentAdultCarcinomaChildChild, PreschoolEpstein-Barr Virus InfectionsFemaleHerpesvirus 4, HumanHIV InfectionsHumansInfantMaleMiddle AgedNasopharyngeal Neoplasms

Identifiers

PMID19810095
PMCPMC2847048
OpenAlexW2118909358

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.