ReviewVirus genes2009
An update on swine-origin influenza virus A/H1N1: a review.
Review in Virus genes, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed.
- Presence of Microorganisms in the Environment: One Health Approach.Microorganisms · 2025Review
- The global burden of swine influenza and its mitigation.Open veterinary journal · 2025Review
- Distinct negative-sense RNA viruses induce a common set of transcripts encoding proteins forming an extensive network.Journal of virology · 2024Article
- Article
- No association of prion protein gene (Molecular & cellular toxicology · 2022Article
- COVID-19: why not learn from the past?Frontiers of medicine · 2021Article
- Trends and strategies to combat viral infections: A review on FDA approved antiviral drugs.International journal of biological macromolecules · 2021Review
- Emergence of Novel Reassortant H1N1 Avian Influenza Viruses in Korean Wild Ducks in 2018 and 2019.Viruses · 2020Article
- Dangerous Pathogens as a Potential Problem for Public Health.Medicina (Kaunas, Lithuania) · 2020Review
- A Review of Antimicrobial Resistance in Poultry Farming within Low-Resource Settings.Animals : an open access journal from MDPI · 2020Review
- Article
- Essential Oils as Antiviral Agents. Potential of Essential Oils to Treat SARS-CoV-2 Infection: AnInternational journal of molecular sciences · 2020Article
- Communicable Diseases (Including COVID-19)-Induced Global Depression: Caused by Inadequate Healthcare Expenditures, Population Density, and Mass Panic.Frontiers in public health · 2020Article
- Protection against homo and hetero-subtypic influenza A virus by optimized M2e DNA vaccine.Emerging microbes & infections · 2019Article
- Prerequisites for the acquisition of mammalian pathogenicity by influenza A virus with a prototypic avian PB2 gene.Scientific reports · 2017Article
- Genetic and codon usage bias analyses of polymerase genes of equine influenza virus and its relation to evolution.BMC genomics · 2017Article
- Epidemiology and Clinical Complication Patterns of Influenza A (H1N1 Virus) in Northern Saudi Arabia.Infectious disease reports · 2017Article
- Sus scrofa miR-204 and miR-4331 Negatively Regulate Swine H1N1/2009 Influenza A Virus Replication by Targeting Viral HA and NS, Respectively.International journal of molecular sciences · 2017Article
- Influenza viruses - antiviral therapy and resistance.GMS infectious diseases · 2017Review
- Increased risk of A(H1N1)pdm09 influenza infection in UK pig industry workers compared to a general population cohort.Influenza and other respiratory viruses · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Influenza viruses cause annual epidemics and occasional pandemics that have claimed the lives of millions. The emergence of new strains will continue to pose challenges to public health and the scientific communities. The recent flu pandemic caused by a swine-origin influenza virus A/H1N1 (S-OIV) presents an opportunity to examine virulence factors, the spread of the infection and to prepare for major influenza outbreaks in the future. The virus contains a novel constellation of gene segments, the nearest known precursors being viruses found in swine and it probably arose through reassortment of two viruses of swine origin. Specific markers for virulence can be evaluated in the viral genome, PB1-F2 is a molecular marker of pathogenicity but is not present in the new S-OIV. While attention was focused on a threat of an avian influenza H5N1 pandemic emerging from Asia, a novel influenza virus of swine origin emerged in North America, and is now spreading worldwide. However, S-OIV demonstrates that even serotypes already encountered in past human pandemics may constitute new pandemic threats. There are concerns that this virus may mutate or reassort with existing influenza viruses giving rise to more transmissible or more pathogenic viruses. The 1918 Spanish flu pandemic virus was relatively mild in its first wave and acquired more virulence when it returned in the winter. Thus preparedness on a global scale against a potential more virulent strain is highly recommended. Most isolates of the new S-OIVs are susceptible to neuraminidase inhibitors, and currently a vaccine against the pandemic strain is being manufactured and will be available this fall. This review summarizes the current information on the new pandemic swine-origin influenza virus A/H1N1.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.