ArticleIntensive care medicine2010
Thyroid hormone and cortisol concentrations after congenital heart surgery in infants younger than 3 months of age.
Article in Intensive care medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Comparison of Adrenal Suppression between Etomidate and Dexmedetomidine in Children with Congenital Heart Disease.Medical science monitor : international medical journal of experimental and clinical research · 2015Trial
- Prolonged anesthesia duration is associated with postoperative thyroid hormone reduction in pediatric surgical patients: a retrospective cohort study.Frontiers in pediatrics · 2026Article
- Achieving Neuroprotection in the Setting of Early Extubation During Infant Cardiac Surgery: A Prospective, Randomized, and Blinded Study.Cardiology research · 2025Article
- Stress Markers, Executive Functioning, and Resilience Among Early Adolescents With Complex Congenital Heart Disease.JAMA network open · 2024Article
- Patterns and Determinants of Change in Cortisol Levels and Thyroid Function as a Function of Cardiac Risk in Children Undergoing Cardiac Surgery.International journal of pediatrics · 2022Article
- Adrenal insufficiency in neonates undergoing cardiopulmonary bypass and postoperative hypothalamic-pituitary-adrenal function after prophylactic glucocorticoids.Journal of perinatology : official journal of the California Perinatal Association · 2019Observational
- Cortisol Response in Children After Second Cardiopulmonary Bypass.Pediatric cardiology · 2019Article
- CHD associated with syndromic diagnoses: peri-operative risk factors and early outcomes.Cardiology in the young · 2016Review
- Article
- Adrenal insufficiency in children undergoing heart surgery does not correlate with more complex postoperative course.Pediatric cardiology · 2013Article
- Year in review in Intensive Care Medicine 2010: III. ARDS and ALI, mechanical ventilation, noninvasive ventilation, weaning, endotracheal intubation, lung ultrasound and paediatrics.Intensive care medicine · 2011Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate associations between thyroid hormone and cortisol concentrations after cardiac surgery and postoperative intensive care course.
methodsProspective observational study of 52 infants <3 months of age following congenital heart surgery.
resultsInfants with low tri-iodothyronine (< or =3.7 pmol/l) or high cortisol concentration on postoperative admission to the paediatric intensive care unit (PICU) were more likely to have a high inotrope requirement on postoperative day 2 (p = 0.003 and p = 0.0006, respectively) or need mechanical ventilation for longer than 96 h (p = 0.04 and p = 0.002, respectively). Total cortisol concentration < 200 nmol/l was found in 16 (31%) infants. There was no association between low cortisol and postoperative complications.
conclusionsInfants <3 months of age with low tri-iodothyronine or high cortisol concentration on PICU admission have a more complicated PICU course. Low cortisol concentration is common in the early postoperative period, but is not associated with postoperative complications.
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