ArticleBiointerphases2008
Molecular simulation of protein-surface interactions: benefits, problems, solutions, and future directions.
Article in Biointerphases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Identification of Novel Tyrosinase Inhibitors with Nanomolar Potency Using Virtual Screening Approaches.Current topics in medicinal chemistry · 2025Article
- Article
- Computational Insights into the Adsorption of Ligands on Gold Nanosurfaces.The journal of physical chemistry. A · 2023Article
- Nanoscale Topographical Effects on the Adsorption Behavior of Bone Morphogenetic Protein-2 on Graphite.International journal of molecular sciences · 2022Article
- Developments and Ongoing Challenges for Analysis of Surface-Bound Proteins.Annual review of analytical chemistry (Palo Alto, Calif.) · 2021Article
- Enzyme Models-From Catalysis to Prodrugs.Molecules (Basel, Switzerland) · 2021Review
- Tuning Structure and Dynamics of Blue Copper Azurin Junctions via Single Amino-Acid Mutations.Biomolecules · 2019Article
- Prediction of membrane separation efficiency for hydrophobic and hydrophilic proteins : A coarse-grained Brownian dynamics simulation study.Journal of molecular modeling · 2019Article
- Surface Analysis: From Single Crystals to Biomaterials.Surface and interface analysis : SIA · 2018Article
- Amino acid adsorption on anatase (101) surface at vacuum and aqueous solution: a density functional study.Journal of molecular modeling · 2018Article
- The effects of tether placement on antibody stability on surfaces.The Journal of chemical physics · 2017Article
- Lysozyme orientation and conformation on MoSBiointerphases · 2017Article
- Application of advanced sampling and analysis methods to predict the structure of adsorbed protein on a material surface.Biointerphases · 2017Article
- Interplay between adsorbed peptide structure, trapped water, and surface hydrophobicity.Biointerphases · 2017Article
- Parameterization of an interfacial force field for accurate representation of peptide adsorption free energy on high-density polyethylene.Biointerphases · 2015Article
- Orientation-Controlled Electrocatalytic Efficiency of an Adsorbed Oxygen-Tolerant Hydrogenase.PloS one · 2015Article
- Perspectives on the simulation of protein-surface interactions using empirical force field methods.Colloids and surfaces. B, Biointerfaces · 2014Article
- Quantification of the influence of protein-protein interactions on adsorbed protein structure and bioactivity.Colloids and surfaces. B, Biointerfaces · 2013Article
- Molecular dynamics simulations of DPPC bilayers using "LIME", a new coarse-grained model.The journal of physical chemistry. B · 2013Article
- α-helix to β-hairpin transition of human amylin monomer.The Journal of chemical physics · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
While the importance of protein adsorption to materials surfaces is widely recognized, little is understood at this time regarding how to design surfaces to control protein adsorption behavior. All-atom empirical force field molecular simulation methods have enormous potential to address this problem by providing an approach to directly investigate the adsorption behavior of peptides and proteins at the atomic level. As with any type of technology, however, these methods must be appropriately developed and applied if they are to provide realistic and useful results. Three issues that are particularly important for the accurate simulation of protein adsorption behavior are the selection of a valid force field to represent the atomic-level interactions involved, the accurate representation of solvation effects, and system sampling. In this article, each of these areas is addressed and future directions for continued development are presented.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.